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Reversible splenial lesions presenting in conjunction with febrile illness: a case series and literature review

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Abstract

Transient restricted diffusion and increased T2 signal intensity within the splenium of the corpus callosum is an increasingly recognized albeit uncommon imaging feature in the setting of acute encephalitis and antecedent viral illness. This review will discuss three index cases obtained from an institutional databank. Additionally, the current understanding of the underlying neurophysiologic pathogenesis will be discussed together with differential clinical and imaging diagnostic considerations, treatment options, and outcome metrics.

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Authors and Affiliations

  1. Department of Radiology, Henry Ford Health System, 2799 West Grand Blvd, Detroit, MI, 48202, USA

    David Lin & Matthew Rheinboldt

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  1. David Lin
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  2. Matthew Rheinboldt
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Correspondence to Matthew Rheinboldt.

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Lin, D., Rheinboldt, M. Reversible splenial lesions presenting in conjunction with febrile illness: a case series and literature review. Emerg Radiol 24, 599–604 (2017). https://doi.org/10.1007/s10140-017-1516-4

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  • DOI: https://doi.org/10.1007/s10140-017-1516-4

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