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Liver trauma grading and biochemistry tests

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Abstract

Among solid organ blunt traumas, the liver and spleen are mostly subject to injury. In addition, the liver is also commonly injured in penetrating traumas because of its size, location, and the ease of injury to the “Glisson Capsule”. Several enzymes are known to be elevated following trauma. In our study, we evaluated the correlation between the levels of serum aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and gamma-glutamyl transpeptidase in 57 patients with blunt trauma to the liver and compared these values to the American Association for the Surgery of Trauma trauma grading system. Additionally, we compared the enzyme level elevations in these patients to the enzyme levels of 29 healthy subjects. As expected, we found significant elevations in enzyme levels of trauma patients compared to the control group. The calculated point estimates were not significantly different between grades 1 and 2 trauma. However, grade 3 trauma group showed a significant increase in enzyme levels.

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References

  1. Moore EE, Shackford SR, Pachter HL, McAninch JW, Browner BD, Champion HR et al (1989) Organ injury scaling: spleen, liver, and kidney. J Trauma 29:1664–6

    Article  PubMed  CAS  Google Scholar 

  2. Moore EE, Cogbill TH, Jurkovich GJ, Shackford SR, Malangoni MA, Champion HR (1995) Organ injury scaling: spleen and liver. J Trauma 1994(38):323–4

    Article  Google Scholar 

  3. Ritchie AH, Williscroft DM (2006) Elevated liver enzymes as a predictor of liver injury in stable blunt abdominal trauma patients: case report and systematic review of the literature. Can J Rural Med 11(4):283–287

    PubMed  Google Scholar 

  4. Cogbill T, Moore E, Feliciano D et al (1992) Hepatic enzyme response and hyperpyrexia after severe liver injury. Am Surg 58:395–9

    PubMed  CAS  Google Scholar 

  5. Strawn T, Williams H, Flint L (1980) Prognostic significance of serum biochemical changes following liver trauma. Am Surg 46:111–5

    PubMed  CAS  Google Scholar 

  6. Risholm L, Sullivan L (1966) Changes in the transaminase and phosphatase activity of the blood and the occurrence of haemobilia following experimental liver trauma in the rabbit. Acta Chir Scand 131:495–8

    PubMed  CAS  Google Scholar 

  7. Sahdev P, Garramone RR Jr, Scwartz RJ, Steelman SR, Jacobs LM (1991) Evaluation of liver function tests in screening for intra-abdominal injuries. Ann Emerg Med 20(8):838–41

    Article  PubMed  CAS  Google Scholar 

  8. Aragon G, Younossi ZAM (2010) When and how to evaluate mildly elevated liver enzymes in apparently healthy patients. Cleve Clin J Med 77(3):195–204

    Article  PubMed  Google Scholar 

  9. Haftel A, Lev R, Manhour G et al (1988) Abdominal CT scanning in pediatric blunt trauma. Ann Emerg Med 17:684–689

    Article  PubMed  CAS  Google Scholar 

  10. Oldham KT, Guice KS, Kaufman RA (1984) Blunt hepatic injury and elevated hepatic enzymes: a clinical correlation in children. J Pediatr Surg 19:457–461

    Article  PubMed  CAS  Google Scholar 

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The authors declare that they have no conflict of interest.

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Correspondence to Gozde Arslan.

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Arslan, G., Gemici, A.A., Yirgin, I.K. et al. Liver trauma grading and biochemistry tests. Emerg Radiol 20, 379–384 (2013). https://doi.org/10.1007/s10140-013-1140-x

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  • DOI: https://doi.org/10.1007/s10140-013-1140-x

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