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Promoting R & D in Photobiological Hydrogen Production Utilizing Mariculture-Raised Cyanobacteria

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Abstract

This review article explores the potential of using mariculture-raised cyanobacteria as solar energy converters of hydrogen (H2). The exploitation of the sea surface for large-scale renewable energy production and the reasons for selecting the economical, nitrogenase-based systems of cyanobacteria for H2 production, are described in terms of societal benefits. Reports of cyanobacterial photobiological H2 production are summarized with respect to specific activity, efficiency of solar energy conversion, and maximum H2 concentration attainable. The need for further improvements in biological parameters such as low-light saturation properties, sustainability of H2 production, and so forth, and the means to overcome these difficulties through the identification of promising wild-type strains followed by optimization of the selected strains using genetic engineering are also discussed. Finally, a possible mechanism for the development of economical large-scale mariculture operations in conjunction with international cooperation and social acceptance is outlined.

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References

  • DG Adams (2000) ArticleTitleHeterocyst formation in cyanobacteria Curr Opinion Microbiol 3 618–624 Occurrence Handle10.1016/S1369-5274(00)00150-8

    Article  Google Scholar 

  • J Appel S Phunpruch K Steinmüller R Schulz (2000) ArticleTitleThe bidirectional hydrogenase of Synechocystis sp. PCC 6803 works as an electron valve during photosynthesis Arch Microbiol 173 333–338 Occurrence Handle10.1007/s002030000139

    Article  Google Scholar 

  • JR Benemann (2000) ArticleTitleHydrogen production by microalgae J Appl Phycol 12 291–300 Occurrence Handle10.1023/A:1008175112704

    Article  Google Scholar 

  • B Bergman JR Gallon AN Rai LJ Stal (1997) ArticleTitleN2 fixation by non-heterocystous cyanobacteria FEMS Microbiol Rev 19 139–185 Occurrence Handle10.1016/S0168-6445(96)00028-9

    Article  Google Scholar 

  • I Berman-Frank P Lundgren P Falkowski (2003) ArticleTitleNitrogen fixation and photosynthetic oxygen evolution in cyanobacteria Res Microbiol 154 157–164 Occurrence Handle10.1016/S0923-2508(03)00029-9

    Article  Google Scholar 

  • H Böhme (1998) ArticleTitleRegulation of nitrogen fixation in heterocyst-forming cyanobacteria Trends Plant Sci 3 346–351 Occurrence Handle10.1016/S1360-1385(98)01290-4

    Article  Google Scholar 

  • Cammack R, Frey M, Robson R, eds (2001) Hydrogen as a Fuel-Learning from Nature (London and New York: Taylor & Francis)

  • JR Chisnell R Premakumar PE Bishop (1988) ArticleTitlePurification of a second alternative nitrogenase from a nifHDK deletion strain of Azotobacter vinelandii J Bacteriol 170 27–33

    Google Scholar 

  • M Colon-Lopez DM Sherman LA Sherman (1997) ArticleTitleTranscriptional and translational regulation of nitrogenase in light-dark- and continuous-light grown cultures of the unicellular cyanobacterium Cyanothece sp. strain ATCC 51142 J Bacteriol 179 4319–4327

    Google Scholar 

  • A Cumino L Curatti L Giarrocco GL Salerno (2002) ArticleTitleSucrose metabolism: Anabaena sucrose-phosphate synthase and sucrose-phosphate phosphatase define minimal functional domains shuffled during evolution FEBS Lett 517 19–23 Occurrence Handle10.1016/S0014-5793(02)02516-4

    Article  Google Scholar 

  • Cyanobase: http://www.kazusa.or.jp/cyano/cyano.html

  • D Das TN Veziroglu (2001) ArticleTitleHydrogen production by biological processes: a survey of literature Int J Hydrogen Energy 26 13–28 Occurrence Handle10.1016/S0360-3199(00)00058-6

    Article  Google Scholar 

  • Dutta D, De D, Chaudhuri S, Bhattacharya SK (2005) Hydrogen production by cyanobacteria. Microbial Cell Factories 4, Art. No. 36

  • RR Eady (1996) ArticleTitleStructure-function relationships of alternative nitrogenases Chem Rev 96 3013–3030 Occurrence Handle10.1021/cr950057h

    Article  Google Scholar 

  • RR Eady (2003) ArticleTitleCurrent status of structure function relationships of vanadium nitrogenase Coord Chem Rev 237 23–30 Occurrence Handle10.1016/S0010-8545(02)00248-5

    Article  Google Scholar 

  • S Ehira M Ohmori N Sato (2003) ArticleTitleGenome-wide expression analysis of the responses to nitrogen deprivation in the heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120 DNA Res 10 97–113 Occurrence Handle10.1093/dnares/10.3.97

    Article  Google Scholar 

  • O Einsle FA Tezcan SLA Andrade B Schmid M Yoshida JB Howard DC Rees (2002) ArticleTitleNitrogenase MoFe-protein at 1.16 angstrom resolution: a central ligand in the FeMo-cofactor Science 297 1696–1700 Occurrence Handle10.1126/science.1073877

    Article  Google Scholar 

  • J Elhai CP Wolk (1988) ArticleTitleConjugal transfer of DNA to cyanobacteria Methods Enzymol 167 747–754 Occurrence Handle10.1016/0076-6879(88)67086-8

    Article  Google Scholar 

  • A Ernst H Kirschenlohr J Diez P Böger (1984) ArticleTitleGlycogen-content and nitrogenase activity in Anabaena variabilis Arch Microbiol 140 120–125 Occurrence Handle10.1007/BF00454913

    Article  Google Scholar 

  • Y Fujita K Ohki A Murakami (2001) “Acclimation of photosynthetic light energy conversion to the light environments” LC Rai JP Gaur (Eds) Algal Adaptation to Environmental Stresses: Physiological, Biochemical and Molecular Mechanism Springer-Verlag Berlin/Heidelberg 135–171

    Google Scholar 

  • JR Gallon (2001) ArticleTitleN2 fixation in phototrophs: adaptation to a specialized way of life Plant Soil 230 39–48 Occurrence Handle10.1023/A:1004640219659

    Article  Google Scholar 

  • ML Ghirardi JP Zhang JW Lee T Flynn M Seibert E Greenbaum A Melis (2000) ArticleTitleMicroalgae: a green source of renewable H2 Trends Biotechnol 18 506–511 Occurrence Handle10.1016/S0167-7799(00)01511-0

    Article  Google Scholar 

  • ML Ghirardi PW King MC Posewitz PC Maness A Fedorov K Kim J Cohen K Schulten M Seibert (2005) ArticleTitleApproaches to developing biological H2-photoproducing organisms and processes Biochem Soc Trans 33 70–72 Occurrence Handle10.1042/BST0330070

    Article  Google Scholar 

  • JW Golden HS Yoon (2003) ArticleTitleHeterocyst development in Anabaena Curr Opin Microbiol 6 557–563 Occurrence Handle10.1016/j.mib.2003.10.004

    Article  Google Scholar 

  • DO Hall SA Markov Y Watanabe K Rao (1995) ArticleTitleThe potential applications of cyanobacterial photosynthesis for clean technologies Photosyn Res 46 159–167 Occurrence Handle10.1007/BF00020426

    Article  Google Scholar 

  • PC Hallenbeck JR Benemann (2002) ArticleTitleBiological hydrogen production; fundamentals and limiting processes Int J Hydrogen Energy 27 1185–1193 Occurrence Handle10.1016/S0360-3199(02)00131-3

    Article  Google Scholar 

  • Hallenbeck PC, Kochian LV, Weissman JC, Benemann JR (1978) Solar energy conversion with hydrogen-producing cultures of the blue-green alga, Anabaena cylindrica. Biotechnol Bioengineer Symp No 8, 283–297

    Google Scholar 

  • A Hansel P Lindblad (1998) ArticleTitleTowards optimization of cyanobacteria as biotechnologically relevant producers of molecular hydrogen, a clean and renewable energy source Appl Microbiol Biotechnol 50 153–160 Occurrence Handle10.1007/s002530051270

    Article  Google Scholar 

  • T Happe K Schütz H Böhme (2000) ArticleTitleTranscriptional and mutational analysis of the uptake hydrogenase of the filamentous cyanobacterium Anabaena variabilis ATCC 29413 J Bacteriol 182 1624–1631 Occurrence Handle10.1128/JB.182.6.1624-1631.2000

    Article  Google Scholar 

  • T Happe A Hemschemeier M Winkler A Kaminski (2002) ArticleTitleHydrogenases in green algae: do they save the algae’s life and solve our energy problems? Trends Plant Sci 7 246–250 Occurrence Handle10.1016/S1360-1385(02)02274-4

    Article  Google Scholar 

  • A Herrero AM Muro-Pastor E Flores (2001) ArticleTitleNitrogen control in cyanobacteria J Bacteriol 183 411–425 Occurrence Handle10.1128/JB.183.2.411-425.2001

    Article  Google Scholar 

  • Houghton JT, Meira Filho LG, Callander BA, Harris N, Kattenberg A, Maskell K, eds (1996) Climate Change 1995. The Science of Climate Change (Cambridge, UK: Cambridge University Press)

  • Houghton JT, Ding Y, Griggs DJ, Noguer M, van der Linden PJ, Dai X, Maskell K, Johnson CA, eds (2001) Climate Change 2001. The Scientific Basis (Cambridge, UK: Cambridge University Press)

  • RY Igarashi LC Seefeldt (2003) ArticleTitleNitrogen fixation: the mechanism of the Mo-dependent nitrogenase Crit Rev Biochem Mol Biol 38 351–384 Occurrence Handle10.1080/10409230391036766

    Article  Google Scholar 

  • TW Jeffries H Timourian RL Ward (1978) ArticleTitleHydrogen production by Anabaena cylindrica: effects of varying ammonium and ferric ions, pH, and light Appl Environ Microbiol 35 704–710

    Google Scholar 

  • Joint Genome Institute, http://genome.jgi-psf.org/mic_home.html

  • T Kaneko Y Nakamura CP Wolk T Kuritz S Sasamoto A Watanabe M Iriguchi A Ishikawa K Kawashima T Kimura Y Kishida M Kohara M Matsumoto A Matsuno A Muraki N Nakazaki S Shimpo M Sugimoto M Takazawa M Yamada M Yasuda S Tabata (2001) ArticleTitleComplete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120 DNA Res 8 227–253 Occurrence Handle10.1093/dnares/8.5.227

    Article  Google Scholar 

  • IK Kapdan F Kargi (2006) ArticleTitleBio-hydrogen production from waste materials Enzyme Microbial Technol 38 569–582 Occurrence Handle10.1016/j.enzmictec.2005.09.015

    Article  Google Scholar 

  • T Kentemich G Danneberg B Hundeshagen H Bothe (1988) ArticleTitleEvidence for the occurrence of the alternative, vanadium-containing nitrogenase in the cyanobacterium Anabaena variabilis FEMS Microbiol Lett 51 19–24 Occurrence Handle10.1111/j.1574-6968.1988.tb02960.x

    Article  Google Scholar 

  • HS Kheshgi RC Prince G Marland (2000) ArticleTitleThe potential of biomass fuels in the context of global climate change: focus on transportation fuels Annu Rev Energy Environ 25 199–244 Occurrence Handle10.1146/annurev.energy.25.1.199

    Article  Google Scholar 

  • O Kruse J Rupprecht JR Mussgnug GC Dismukes B Hankamer (2005) ArticleTitlePhotosynthesis: a blueprint for solar energy capture and biohydrogen production technologies Photochem Photobiol Sci 4 957–970 Occurrence Handle10.1039/b506923h

    Article  Google Scholar 

  • D Kumar HD Kumar (1991) ArticleTitleEffect of monochromatic lights on nitrogen-fixation and hydrogen evolution in the isolated heterocysts of Anabaena sp. strain CA Int J Hydrogen Energy 16 397–401 Occurrence Handle10.1016/0360-3199(91)90138-9

    Article  Google Scholar 

  • S Kumazawa H Asakawa (1995) ArticleTitleSimultaneous production of H2 and O2 in closed vessels by marine cyanobacterium Anabaena sp. TU37-1 under high-cell-density conditions Biotechnol Bioeng 46 396–398 Occurrence Handle10.1002/bit.260460414

    Article  Google Scholar 

  • S Kumazawa A Mitsui (1981) ArticleTitleCharacterization and optimization of hydrogen photoproduction by a saltwater blue-green alga, Oscillatoria sp. Miami BG7. I. Enhancement through limiting the supply of nitrogen nutrients Int J Hydrogen Energy 6 339–348 Occurrence Handle10.1016/0360-3199(81)90060-4

    Article  Google Scholar 

  • S Kumazawa A Mitsui (1985) ArticleTitleComparative amperometric study of uptake hydrogenase and hydrogen photoproduction activities between heterocystous cyanobacterium Anabaena cylindrica B629 and nonheterocystous cyanobacterium Oscillatoria sp. strain Miami BG7 Appl Environ Microbiol 50 287–291

    Google Scholar 

  • S Kumazawa A Mitsui (1994) ArticleTitleEfficient hydrogen photoproduction by synchronously grown cells of a marine cyanobacterium, Synechococcus sp. Miami BG-043511, under high cell-density conditions Biotechnol Bioeng 44 854–858 Occurrence Handle10.1002/bit.260440711

    Article  Google Scholar 

  • DB Levin L Pitt M Love (2004) ArticleTitleBiohydrogen production: prospects and limitations to practical application Int J Hydrogen Energy 29 173–185 Occurrence Handle10.1016/S0360-3199(03)00094-6

    Article  Google Scholar 

  • P Lindberg K Schütz T Happe P Lindblad (2002) ArticleTitleA hydrogen-producing, hydrogenase-free mutant strain of Nostoc punctiforme ATCC 29133 Int J Hydrogen Energy 27 1291–1296 Occurrence Handle10.1016/S0360-3199(02)00121-0

    Article  Google Scholar 

  • P Lindblad K Christensson P Lindberg A Fedorov F Pinto A Tsygankov (2002) ArticleTitlePhotoproduction of H2 by wildtype Anabaena PCC 7120 and a hydrogen uptake deficient mutant: from laboratory experiments to outdoor culture Int J Hydrogen Energy 27 1271–1281 Occurrence Handle10.1016/S0360-3199(02)00111-8

    Article  Google Scholar 

  • D Madamwar N Garg V Shah (2000) ArticleTitleCyanobacterial hydrogen production World J Microbiol Biotechnol 16 757–767 Occurrence Handle10.1023/A:1008919200103

    Article  Google Scholar 

  • H Masukawa MochimaruM Sakurai (2002a) ArticleTitleDisruption of the uptake hydrogenase gene, but not of the bidirectional hydrogenase gene, leads to enhanced photobiological hydrogen production by nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120 Appl Microbiol Biotechnol 58 618–624 Occurrence Handle10.1007/s00253-002-0934-7

    Article  Google Scholar 

  • H Masukawa M Mochimaru H Sakurai (2002b) ArticleTitleHydrogenases and photobiological hydrogen production utilizing nitrogenase system in cyanobacteria Int J Hydrogen Energy 27 1471–1474 Occurrence Handle10.1016/S0360-3199(02)00125-8

    Article  Google Scholar 

  • JC Meeks J Elhai (2002) ArticleTitleRegulation of cellular differentiation in filamentous cyanobacteria in free-living and plant-associated symbiotic growth states Microbiol Mol Biol Rev 66 94–121 Occurrence Handle10.1128/MMBR.66.1.94-121.2002

    Article  Google Scholar 

  • A. Melis (2002) ArticleTitleGreen alga hydrogen production: progress, challenges and prospects Int J Hydrogen Energy 27 1217–1228 Occurrence Handle10.1016/S0360-3199(02)00110-6

    Article  Google Scholar 

  • A Melis T Happe (2004) ArticleTitleTrails of green alga hydrogen research-from Hans Gaffron to new frontiers Photosyn Res 80 401–409 Occurrence Handle10.1023/B:PRES.0000030421.31730.cb

    Article  Google Scholar 

  • A Melis LP Zhang M Forestier ML Ghirardi M Seibert (2000) ArticleTitleSustained photobiological hydrogen gas production upon reversible inactivation of oxygen evolution in the green alga Chlamydomonas reinhardtii Plant Physiol 122 127–135 Occurrence Handle10.1104/pp.122.1.127

    Article  Google Scholar 

  • R Mertens A Liese (2004) ArticleTitleBiotechnological applications of hydrogenases Curr Opin Biotechnol 15 343–348 Occurrence Handle10.1016/j.copbio.2004.06.010

    Article  Google Scholar 

  • H Michel M Tellenbach A Boschetti (1983) ArticleTitleA chlorophyll b-less mutant of Chlamydomonas reinhardii lacking in the light-harvesting chlorophyll a/b-protein complex but not in its apoproteins Biochim Biophys Acta 725 417–424 Occurrence Handle10.1016/0005-2728(83)90182-2

    Article  Google Scholar 

  • LE Mikheeva O Schmitz SV Shestakov H Bothe (1995) ArticleTitleMutants of the cyanobacterium Anabaena variabilis altered in hydrogenase activities Z Naturforsch 50c 505–510

    Google Scholar 

  • HS Misra R Tuli (2000) ArticleTitleDifferential expression of photosynthesis and nitrogen fixation genes in the cyanobacterium Plectonema boryanum Plant Physiol 122 731–736 Occurrence Handle10.1104/pp.122.3.731

    Article  Google Scholar 

  • N Mitome T Suzuki S Hayashi M Yoshida (2004) ArticleTitleThermophilic ATP synthase has a decamer c-ring: indication of noninteger 10:3 H+/ATP ratio and permissive elastic coupling Proc Natl Acad Sci USA 101 12159–12164 Occurrence Handle10.1073/pnas.0403545101

    Article  Google Scholar 

  • A Mitsui EJ Phlips S Kumazawa KI Reddy S Ramachandran T Matsunaga L Haynes H Ikemoto (1983) ArticleTitleProgress in research toward outdoor biological hydrogen-production using solar-energy, sea-water, and marine photosynthetic microorganisms Ann NY Acad Sci 413 514–530 Occurrence Handle10.1111/j.1749-6632.1983.tb47931.x

    Article  Google Scholar 

  • A Mitsui S Kumazawa EJ Phlips KJ Reddy RK Gill T Matsunaga BR Renuka T Kusumi G Reyes-Vasquez K Miyazawa L Haynes H Ikemoto E Duerr CB Leon D Rosner R Sesco E Moffat (1985) “Mass cultivation of algae and photosynthetic bacteria: concepts and application” TK Ghose (Eds) Biotechnology and Bioprocess Engineering United India Press New Delhi 119–155

    Google Scholar 

  • A Mitsui S Kumazawa A Takahashi H Ikemoto S Cao T Arai (1986) ArticleTitleStrategy by which nitrogen-fixing unicellular cyanobacteria grow photoautotrophically Nature 323 720–722 Occurrence Handle10.1038/323720a0

    Article  Google Scholar 

  • Miyake J, Matusnaga T, San Pietro A, eds (2001) Biohydrogen II. An Approach to Environmentally Acceptable Technology (Amsterdam: Pergamon)

    Google Scholar 

  • Miyake J, Igarashi Y, Rögner M, eds (2004) Biohydrogen III. Renewable Energy System by Biological Energy Conversion (Amsterdam: Elsevier)

    Google Scholar 

  • Y Nakajima R Ueda (1997) ArticleTitleImprovement of photosynthesis in dense microalgal suspension by reduction of light harvesting pigment J Appl Phycol 9 503–510

    Google Scholar 

  • CV Ni AF Yakunin IN Gogotov (1990) ArticleTitleInfluence of molybdenum, vanadium, and tungsten on growth and nitrogenase synthesis of the free-living cyanobacterium Anabaena azollae Microbiology 59 395–398

    Google Scholar 

  • InstitutionalAuthorNameOECD/IEA (2000) World Energy Outlook 2000. OECD Publishing Paris

    Google Scholar 

  • M Paumann G Regelsberger C Obinger GA Peschek (2005) ArticleTitleThe bioenergetic role of dioxygen and the terminal oxidase(s) in cyanobacteria Biochim Biophys Acta 1707 231–253 Occurrence Handle10.1016/j.bbabio.2004.12.007

    Article  Google Scholar 

  • EJ Phlips A Mitsui (1983) ArticleTitleRole of light intensity and temperature in the regulation of hydrogen photoproduction by the marine cyanobacterium Oscillatoria sp. strain Miami BG7 Appl Environ Microbiol 45 1212–1220

    Google Scholar 

  • FAL Pinto O Troshina P Lindblad (2002) ArticleTitleA brief look at three decades of research on cyanobacterial hydrogen evolution Int J Hydrogen Energy 27 1209–1215 Occurrence Handle10.1016/S0360-3199(02)00089-7

    Article  Google Scholar 

  • JEW Polle JR Benemann A Tanaka A Melis (2000) ArticleTitlePhotosynthetic apparatus organization and function in the wild type and a chlorophyll b-less mutant of Chlamydomonas reinhardtii. Dependence on carbon source Planta 211 335–344 Occurrence Handle10.1007/s004250000279

    Article  Google Scholar 

  • RC Prince HS Kheshgi (2005) ArticleTitleThe photobiological production of hydrogen: potential efficiency and effectiveness as a renewable fuel Crit Rev Microbiol 31 19–31 Occurrence Handle10.1080/10408410590912961

    Article  Google Scholar 

  • KK Rao R Cammack (2001) “Producing hydrogen as a fuel” R Cammack M Frey R Robson (Eds) Hydrogen as a Fuel-Learning from Nature Taylor & Francis London and New York 201–230

    Google Scholar 

  • P Razquin S Schmitz ML Peleato MF Fillat C Gomezmoreno H Böhme (1995) ArticleTitleDifferential activities of heterocyst ferredoxin, vegetative cell ferredoxin, and flavodoxin as electron carriers in nitrogen-fixation and photosynthesis in Anabaena sp Photosyn Res 43 35–40 Occurrence Handle10.1007/BF00029460

    Article  Google Scholar 

  • DC Rees JB Howard (2000) ArticleTitleNitrogenase: standing at the crossroads Curr Opin Chem Biol 4 559–566 Occurrence Handle10.1016/S1367-5931(00)00132-0

    Article  Google Scholar 

  • R Robson (2001) “Biodiversity of hydrogenases” R Cammack M Frey R Robson (Eds) Hydrogen as a Fuel-Learning from Nature Taylor & Francis London and New York 9–32

    Google Scholar 

  • H Sakurai H Masukawa S Dawar F Yoshino (2004) “Photobiological hydrogen production by cyanobacteria utilizing nitrogenase systems-present status and future development” J Miyake Y Igarashi M Rögner (Eds) Biohydrogen III. Renewable Energy System by Biological Energy Conversion Elsevier Amsterdam 84–93

    Google Scholar 

  • K Schütz T Happe O Troshina P Lindblad E Leitao P Oliveira P Tamagnini (2004) ArticleTitleCyanobacterial H2 production-a comparative analysis Planta 218 350–359 Occurrence Handle10.1007/s00425-003-1113-5

    Article  Google Scholar 

  • L Serebriakova NA Zorin P Lindblad (1994) ArticleTitleReversible hydrogenase in Anabaena variabilis ATCC-29413. Presence and localization in non-N2-fixing cells Arch Microbiol 161 140–144

    Google Scholar 

  • RL Smith D Kumar XK Zhang FR Tabita C Baalen Particlevan (1985) ArticleTitleH2, N2, and O2 metabolism by isolated heterocysts from Anabaena sp. strain CA J Bacteriol 162 565–570

    Google Scholar 

  • WDP Stewart HW Pearson (1970) ArticleTitleEffects of aerobic and anaerobic conditions on growth and metabolism of blue-green algae Proc Roy Soc 175B 293–311

    Google Scholar 

  • DA Sveshnikov NV Sveshnikova KK Rao DO Hall (1997) ArticleTitleHydrogen metabolism of mutant forms of Anabaena variabilis in continuous cultures and under nutritional stress FEMS Microbiol Lett 147 297–301 Occurrence Handle10.1111/j.1574-6968.1997.tb10257.x

    Article  Google Scholar 

  • P Tamagnini R Axelsson P Lindberg F Oxelfelt R Wünschiers P Lindblad (2002) ArticleTitleHydrogenases and hydrogen metabolism of cyanobacteria Microbiol Mol Biol Rev 66 1–20 Occurrence Handle10.1128/MMBR.66.1.1-20.2002

    Article  Google Scholar 

  • A Tanaka H Ito R Tanaka NK Tanaka K Yoshida K Okada (1998) ArticleTitleChlorophyll a oxygenase (CAO) is involved in chlorophyll b formation from chlorophyll a Proc Natl Acad Sci USA 95 12719–12723 Occurrence Handle10.1073/pnas.95.21.12719

    Article  Google Scholar 

  • FA Tezcan JT Kaiser D Mustafi MY Walton JB Howard DC Rees (2005) ArticleTitleNitrogenase complexes: Multiple docking sites for a nucleotide switch protein Science 309 1377–1380 Occurrence Handle10.1126/science.1115653

    Article  Google Scholar 

  • T Thiel (1993) ArticleTitleCharacterization of genes for an alternative nitrogenase in the cyanobacterium Anabaena variabilis J Bacteriol 175 6276–6286

    Google Scholar 

  • T Thiel B Pratte (2001) ArticleTitleEffect on heterocyst differentiation of nitrogen fixation in vegetative cells of the cyanobacterium Anabaena variabilis ATCC 29413 J Bacteriol 183 280–286 Occurrence Handle10.1128/JB.183.1.280-286.2001

    Article  Google Scholar 

  • AS Tsygankov LT Serebryakova DA Sveshnikov KK Rao IN Gogotov DO Hall (1997) ArticleTitleHydrogen photoproduction by three different nitrogenases in whole cells of Anabaena variabilis and the dependence on pH Int J Hydrogen Energy 22 859–867 Occurrence Handle10.1016/S0360-3199(96)00242-X

    Article  Google Scholar 

  • AA Tsygankov AS Fedorov SN Kosourov KK Rao (2002) ArticleTitleHydrogen production by cyanobacteria in an automated outdoor photobioreactor under aerobic conditions Biotechnol Bioeng 80 777–783 Occurrence Handle10.1002/bit.10431

    Article  Google Scholar 

  • Turina P, Samoray D, Gräber P (2003) H+/ATP ratio of proton transport-coupled ATP synthesis and hydrolysis catalysed by CF0F1-liposomes. EMBO J 22, 418-426

    Google Scholar 

  • UNFCCC: Intergovernmental Panel on Climate Change, WMO and UNEP. http://www.ipcc.ch/index.htm (see also http://unfccc.int/2860.php) (as of June 2006)

  • L Vasilyeva M Miyake E Khatipov T Wakayama M Sekine M Hara E Nakada Y Asada J Miyake (1999) ArticleTitleEnhanced hydrogen production by a mutant of Rhodobacter sphaeroides having an altered light-harvesting system J Biosci Bioeng 87 619–624 Occurrence Handle10.1016/S1389-1723(99)80124-8

    Article  Google Scholar 

  • PM Vignais A Colbeau (2004) ArticleTitleMolecular biology of microbial hydrogenases Curr Issues Mol Biol 6 159–188

    Google Scholar 

  • PM Vignais B Billoud J Meyer (2001) ArticleTitleClassification and phylogeny of hydrogenases FEMS Microbiol Rev 25 455–501

    Google Scholar 

  • PM Vitousek K Cassman C Cleveland T Crews CB Field NB Grimm RW Howarth R Marino L Martinelli EB Rastetter JI Sprent (2002) ArticleTitleTowards an ecological understanding of biological nitrogen fixation Biogeochemistry 57 1–45 Occurrence Handle10.1023/A:1015798428743

    Article  Google Scholar 

  • Watson RT and the Core Writing Team, eds (2001) Climate Change 2001: Synthesis Report (Cambridge, UK: Cambridge University Press)

  • JC Weissman JR Benemann (1977) ArticleTitleHydrogen production by nitrogen-fixing cultures of the blue-green alga, Anabaena cylindrica Appl Environ Microbiol 33 123–131

    Google Scholar 

  • CP Wolk (2000) “Heterocyst formation in Anabaena” YV Brun LJ Shimkets (Eds) Prokaryotic Development American Society for Microbiology Washington, DC 83–104

    Google Scholar 

  • AF Yakunin CV Ni IN Gogotov (1991) ArticleTitleEffect of molybdenum, vanadium, and tungsten on the growth of Anabaena variabilis and its synthesis of nitrogenases Microbiology 60 52–56

    Google Scholar 

  • Yoshino F, Ikeda H, Masukawa H, Sakurai H (2006) High photobiological hydrogen production activity of a Nostoc sp. PCC 7422 uptake hydrogenase-deficient mutant with high nitrogenase activity. Marine Biotechnol. DOI: 10.1007/s10126-006-6035-3

  • Zaborsky OR, ed (1998) Biohydrogen (New York and London: Plenum Press)

  • CC Zhang S Laurent S Sakr L Peng S Bedu (2006) ArticleTitleHeterocyst differentiation and pattern formation in cyanobacteria: a chorus of signals Mol Microbiol 59 367–375 Occurrence Handle10.1111/j.1365-2958.2005.04979.x

    Article  Google Scholar 

Special Issues of Journals

  • Int J Hydrogen Energy 27 (11-12) (2002) Special issue of selected papers, Biohydrogen 2002, van Niel EWJ, Janssen M, Lindblad P, Barten H, Reith JH, Wijffels RH, eds.

  • Biochem Soc Trans 33 (1) (2005) Special issue of International Hydrogenases Conference 2004, Cammack, R, Sargent F, eds.

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Acknowledgments

We thank Dr. Susan Carlson for carefully reading the manuscript. This work was supported in part by the MEXT grant Venture (2001-2005) to H.S., Grants for Special Research Projects, Waseda University (2004A-085, 2005B-083) to H.S., and Grants-in-Aid for Scientific Research from JSPS (16.9494) to H.M.

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  1. Department of Biology, School of Education, and Major in Bioscience and Biomedical Engineering, Graduate School of Science and Engineering, Waseda University, Nishiwaseda 1, Shinjuku, Tokyo, 169-8050, Japan

    Hidehiro Sakurai

  2. Department of Biological Sciences, Kanagawa University, 2946 Tsuchiya, Hiratsuka, Kanagawa, 259-1293, Japan

    Hajime Masukawa

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Sakurai, H., Masukawa, H. Promoting R & D in Photobiological Hydrogen Production Utilizing Mariculture-Raised Cyanobacteria. Mar Biotechnol 9, 128–145 (2007). https://doi.org/10.1007/s10126-006-6073-x

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  • DOI: https://doi.org/10.1007/s10126-006-6073-x

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