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Cutaneous vascular lesions in the pediatric population: a review of laser surgery applications and lesion-specific device parameters

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Abstract

Laser surgery is becoming an increasingly efficacious and customizable treatment modality for the management of pediatric vascular lesions. Proper use requires a thorough understanding of the scientific principles of laser surgery and knowledge of the various lasers available. Moreover, each laser has a multitude of settings that can be employed to properly target the lesion at hand. Each patient will present with unique challenges and variations in the presentation of their vascular lesion. This requires understanding of the most effective laser to use for each lesion and the factors that may alter the desired device settings. Using key search terms, a literature search was conducted on laser surgery for pediatric vascular lesions using PubMed/MEDLINE and Embase for articles published in English or French. Ultimately, 52 articles met our search criteria. The laser indications, limitations, and settings utilized for each type of vascular lesion were compiled for the purposes of this summative review. Laser surgery is an effective and appropriate option for the treatment of certain pediatric vascular lesions. Knowledge of optimal device parameters in every setting is essential to good clinical practice.

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References

  1. Buckmiller LM, Munson PD, Dyamenahalli U, Dai Y, Richter GT (2010) Propranolol for infantile hemangiomas: early experience at a tertiary vascular anomalies center. Laryngoscope. 120(4):676–681

    Article  CAS  PubMed  Google Scholar 

  2. Bruscino N, Bonan P, Cannarozzo G, Moretti S, Lotti T, Campolmi P (2012) Laser use in infantile hemangiomas, when and how. Dermatol Ther 25(4):314–321

    Article  CAS  PubMed  Google Scholar 

  3. Slaughter KA, Chen T, Williams E 3rd. (2016) Vascular Lesions. Facial Plast Surg Clin North Am 24(4):559–571

    Article  PubMed  Google Scholar 

  4. Krowchuk DP, Frieden IJ, Mancini AJ, Darrow DH, Blei F, Greene AK, Annam A, Baker CN, Frommelt PC, Hodak A (2019) Clinical practice guideline for the management of infantile hemangiomas. Pediatrics. 143(1):e20183475

    Article  PubMed  Google Scholar 

  5. Eivazi B, Werner JA. Extracranial vascular malformations (hemangiomas and vascular malformations) in children and adolescents - diagnosis, clinic, and therapy. GMS Curr Top Otorhinolaryngol Head Neck Surg. 2014;13Doc02

  6. Weber F, Chaudry G, Mulliken J, Voss S. Clinical presentation, imaging characteristics and management of parotid hemangiomas. Pediatr Radiol. 2013;43S442

  7. Atas E, Kesik V, Koc O, Atas H. Clinical features and treatment results of patients with hemangioma. Pediatric Blood and Cancer. s;62S353

  8. Blatt J, McLean TW, Castellino SM, Burkhart CN (2013) A review of contemporary options for medical management of hemangiomas, other vascular tumors, and vascular malformations. Pharmacol Ther 139(3):327–333

    Article  CAS  PubMed  Google Scholar 

  9. Chinnadurai S, Sathe NA, Surawicz T (2016) Laser treatment of infantile hemangioma: a systematic review. Lasers Surg Med 48(3):221–233

    Article  PubMed  Google Scholar 

  10. Cole PD, Sonabend ML, Levy ML (2007) Laser treatment of pediatric vascular lesions. Semin Plast Surg 21(3):159–166

    Article  PubMed  PubMed Central  Google Scholar 

  11. Garza G, Fay A, Rubin PAD (2001) Treatment of pediatric vascular lesions of the eyelid and orbit. Int Ophthalmol Clin 41(4):43–55

    Article  CAS  PubMed  Google Scholar 

  12. Menapace D, Mitkov M, Towbin R, Hogeling M (2016) The changing face of complicated infantile hemangioma treatment. Pediatr Radiol 46(11):1494–1506

    Article  PubMed  Google Scholar 

  13. Higuera S, Gordley K, Metry DW, Stal S (2006) Management of hemangiomas and pediatric vascular malformations. J Craniofac Surg 17(4):783–789

    Article  PubMed  Google Scholar 

  14. Dementieva N, Jones S (2016) The treatment of problematic hemangiomas in children with propranolol and 940nm diode laser. J Pediatr Surg 51(5):863–868

    Article  PubMed  Google Scholar 

  15. Elluru RG (2013) Cutaneous vascular lesions. Facial Plast Surg Clin North Am 21(1):111–126

    Article  PubMed  Google Scholar 

  16. Elluru RG, Azizkhan RG (2006) Cervicofacial vascular anomalies. II Vascular malformations Semin Pediatr Surg 15(2):133–139

    PubMed  Google Scholar 

  17. Cordisco MR (2009) An update on lasers in children. Curr Opin Pediatr 21(4):499–504

    Article  PubMed  Google Scholar 

  18. Burns AJ, Navarro JA (2009) Role of laser therapy in pediatric patients. Plast Reconstr Surg 124(1 Suppl):82e–92e

    Article  CAS  PubMed  Google Scholar 

  19. Barčot Z, Župančić B (2010) Pulsed dye laser treatment of vascular lesions in childhood. Acta Dermatovenerol Croat 18(3):201–208

    PubMed  Google Scholar 

  20. Morelli JG (1998) Use of lasers in pediatric dermatology. Dermatol Clin 16(3):489–495

    Article  CAS  PubMed  Google Scholar 

  21. Adams DM, Lucky AW (2006) Cervicofacial vascular anomalies. I. Hemangiomas and other benign vascular tumors. Semin Pediatr Surg 15(2):124–132

    Article  PubMed  Google Scholar 

  22. Batta K, Goodyear HM, Moss C, Williams HC, Hiller L, Waters R (2002) Randomised controlled study of early pulsed dye laser treatment of uncomplicated childhood haemangiomas: results of a 1-year analysis. Lancet 360(9332):521–527

    Article  PubMed  Google Scholar 

  23. Metry DW, Hebert AA (2000) Benign cutaneous vascular tumors of infancy: when to worry, what to do. Arch Dermatol 136(7):905–914

    Article  CAS  PubMed  Google Scholar 

  24. Azizkhan RG (2003) Laser surgery: new applications for pediatric skin and airway lesions. Curr Opin Pediatr 15(3):243–247

    Article  PubMed  Google Scholar 

  25. Kishi Y, Kikuchi K, Hasegawa M, Ohgushi K, Igarashi A, Hatanaka M, Fujino J, Ikeda H (2018) Dye laser treatment for hemorrhagic vascular lesions. Laser Ther 27(1):61–64

    Article  PubMed  PubMed Central  Google Scholar 

  26. Azizkhan RG (2013) Complex vascular anomalies. Pediatr Surg Int 29(10):1023–1038

    Article  PubMed  Google Scholar 

  27. Chen TS, Eichenfield LF, Friedlander SF (2013) Infantile hemangiomas: an update on pathogenesis and therapy. Pediatrics. 131(1):99–108

    Article  PubMed  Google Scholar 

  28. Nasseri E, Piram M, McCuaig CC, Kokta V, Dubois J, Powell J (2014) Partially involuting congenital hemangiomas: a report of 8 cases and review of the literature. J Am Acad Dermatol 70(1):75–79

    Article  PubMed  Google Scholar 

  29. Nam CH, Kim MH, Hong SP, Park BC (2019) Fractional 532-nm KTP diode laser and 595-nm pulsed dye laser in treatment of facial telangiectatic erythema. J Cosmet Dermatol 18(3):783–787

    Article  PubMed  Google Scholar 

  30. Halachmi S, Israeli H, Ben-Amitai D, Lapidoth M (2014) Treatment of the skin manifestations of hereditary hemorrhagic telangiectasia with pulsed dye laser. Lasers Med Sci 29(1):321–324

    Article  PubMed  Google Scholar 

  31. Adams DM, Hammill A (2014) Other vascular tumors. Semin Pediatr Surg 23(4):173–177

    Article  PubMed  Google Scholar 

  32. Tay YK, Weston WL, Morelli JG (1997) Treatment of pyogenic granuloma in children with the flashlamp-pumped pulsed dye laser. Pediatrics. 99(3):368–370

    Article  CAS  PubMed  Google Scholar 

  33. Fernandez-Vozmediano JM, Carranza-Romero C, Armario-Hita JC (2010) Treatment of telangiectaticum granuloma with Nd:YAG laser. J Am Acad Dermatol 62(3):AB148

    Google Scholar 

  34. Zhang B, Zhang TH, Huang Z, Li Q, Yuan KH, Hu ZQ (2014) Comparison of pulsed dye laser (PDL) and photodynamic therapy (PDT) for treatment of facial port-wine stain (PWS) birthmarks in pediatric patients. Photodiagn Photodyn Ther 11(4):491–497

    Article  Google Scholar 

  35. Tan OT, Gilchrest BA (1988) Laser therapy for selected cutaneous vascular lesions in the pediatric population: a review. Pediatrics. 82(4):652–662

    CAS  PubMed  Google Scholar 

  36. Powell J (1999) Update on hemangiomas and vascular malformations. Curr Opin Pediatr 11(5):457–463

    Article  CAS  PubMed  Google Scholar 

  37. Crivaro P, Piva MMM, Ferrario D, Valeria AM, Kowalczuck A (2017) Pulsed dye laser treatment of vascular malformation, 10 years follow up. Int J Dermatol 56(11):1290

    Google Scholar 

  38. Garden JM, Bakus AD (1993) Clinical efficacy of the pulsed dye laser in the treatment of vascular lesions. J Dermatol Surg Oncol 19(4):321–326

    Article  CAS  PubMed  Google Scholar 

  39. Bae YS, Ng E, Geronemus RG (2016) Successful treatment of two pediatric port wine stains in darker skin types using 595 nm laser. Lasers Surg Med 48(4):339–342

    Article  PubMed  Google Scholar 

  40. Glade RS, Richter GT, James CA, Suen JY, Buckmiller LM (2010) Diagnosis and management of pediatric cervicofacial venous malformations: retrospective review from a vascular anomalies center. Laryngoscope. 120(2):229–235

    Article  PubMed  Google Scholar 

  41. Kono T, Frederick Groff W, Chan HH, Sakurai H, Yamaki T (2009) Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for hypertrophic port-wine stains on the lips. J Cosmet Laser Ther 11(1):11–13

    Article  PubMed  Google Scholar 

  42. Baselga E, Wassef M, Lopez S, Hoffman W, Cordisco M, Frieden IJ (2012) Agminated, eruptive pyogenic granuloma-like lesions developing over congenital vascular stains. Pediatr Dermatol 29(2):186–190

    Article  PubMed  Google Scholar 

  43. Moser CM, Hamsch C (2012) Successful treatment of cutaneous venous malformations in a patient with blue rubber bleb naevus syndrome by Nd:YAG laser. Br J Dermatol 166(5):1143–1145

    Article  CAS  PubMed  Google Scholar 

  44. Murthy AS, Dawson A, Gupta D, Spring S, Cordoro KM (2017) Utility and tolerability of the long-pulsed 1064-nm neodymium:yttrium-aluminum-garnet (LP Nd:YAG) laser for treatment of symptomatic or disfiguring vascular malformations in children and adolescents. J Am Acad Dermatol 77(3):473–479

    Article  CAS  PubMed  Google Scholar 

  45. Rivers JK, Rivers CA, Li MK, Martinka M (2016) Laser therapy for an acquired glomuvenous malformation (glomus tumour): a nonsurgical approach. J Cutan Med Surg 20(1):80–83

    Article  PubMed  Google Scholar 

  46. Phillips CB, Guerrero C, Theos A. Nd:YAG laser offers promising treatment option for familial glomuvenous malformation. Dermatol Online J. 2015;21(4)

  47. Brauer JA, Anolik R, Tzu J, Meehan S, Lieber CD, Geronemus RG (2011) Glomuvenous malformations (familial generalized multiple glomangiomas). Dermatol Online J 17(10):9

    PubMed  Google Scholar 

  48. Trost J, Buckley C, Smidt AC (2015) Long-pulsed neodymium-doped yttrium aluminum garnet laser for glomuvenous malformations in adolescents. Pediatr Dermatol 32(5):e217–e218

    Article  PubMed  Google Scholar 

  49. Vargas-Navia N, Baselga E, Munoz-Garza FZ, Puig L (2017) Congenital plaque-type glomuvenous malformation: 11 years of follow-up and response to treatment with the combined pulsed-dye and neodymium:yttrium-aluminum-garnet laser. Actas Dermosifiliogr 108(1):72–74

    Article  CAS  PubMed  Google Scholar 

  50. Nguyen TV, Becker EM, Miller WA, Browning JC (2014) Plaque-type glomuvenous malformations successfully treated using combined pulsed dye laser and neodymium-doped yttrium aluminum garnet laser. Dermatol Surg 40(1):89–92

    Article  CAS  PubMed  Google Scholar 

  51. Akkaya AD, Oram Y, Demirkesen C (2012) Combined lymphatic and capillary malformation successfully treated with pulsed-dye laser and fractional co2 laser. Eur J Pediatr Dermatol 22(1):39–40

    Google Scholar 

  52. Lai C-H, Hanson SG, Mallory SB (2001) Lymphangioma circumscriptum treated with pulsed dye laser. Pediatr Dermatol 18(6):509–510

    Article  CAS  PubMed  Google Scholar 

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Vazquez, T., Forouzandeh, M., Gurnani, P. et al. Cutaneous vascular lesions in the pediatric population: a review of laser surgery applications and lesion-specific device parameters. Lasers Med Sci 35, 1681–1687 (2020). https://doi.org/10.1007/s10103-020-03058-3

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  • DOI: https://doi.org/10.1007/s10103-020-03058-3

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