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Sensory and motor responses after photobiomodulation associated with physiotherapy in patients with incomplete spinal cord injury: clinical, randomized trial

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Abstract

Complete or incomplete spinal cord injury (SCI) results in permanent neurological deficits due to the interruption of nerve impulses, causing the loss of motor and sensory function, which leads to a reduction in quality of life. The focus of rehabilitation for such individuals is to improve quality of life and promote functional recovery. Photobiomodulation (PBM) has proved to be promising complementary treatment in cases of SCI. The aim of the present study was to investigate the effects of PBM combined with physiotherapy on sensory-motor responses below the level of the injury and quality of life in individuals with SCI. Thirty participants were randomized for allocation to the PBM group (active PBM + physiotherapy) or sham group (sham PBM + physiotherapy). Physiotherapy was administered three times a week. Sensitivity and motor skills were evaluated using the ASIA impairment scale. Quality of life was assessed using the WHOQOL-BREF questionnaire. The data were analyzed with the level of significance set to 5%. Improvements in sensitivity and an increase in the perception of muscle contraction were found in the active PBM group 30 days after treatment compared with the sham group. The results of the WHOQOL-BREF questionnaire revealed a significant difference in general quality of life favoring the active PBM group over the sham group after treatment. Physiotherapy combined with PBM leads to better sensory-motor recovery in patients with SCI as well as a better perception of health and quality of life. Trial registration identifier: NCT 03031223

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Acknowledgments

We thank Universidade Nove de Julho for making the laboratories available for the study.

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Authors and Affiliations

  1. Universidade Nove de Julho, Rua Vergueiro, 235/249 - Liberdade, São Paulo, SP, Brazil

    Fernanda Cordeiro da Silva, Tamiris Silva, Andréa Oliver Gomes, Paulo Roberto da Costa Palácio, Lucas Andreo, Marcela Leticia Leal Gonçalves, Daniela Fátima Teixeira Silva, Anna Carolina Ratto Tempestini Horliana, Lara Jansiski Motta, Raquel Agnelli Mesquita-Ferrari, Kristianne Porta Santos Fernandes & Sandra Kalil Bussadori

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  1. Fernanda Cordeiro da Silva
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  2. Tamiris Silva
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  3. Andréa Oliver Gomes
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  4. Paulo Roberto da Costa Palácio
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  5. Lucas Andreo
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  6. Marcela Leticia Leal Gonçalves
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  7. Daniela Fátima Teixeira Silva
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  8. Anna Carolina Ratto Tempestini Horliana
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  11. Kristianne Porta Santos Fernandes
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  12. Sandra Kalil Bussadori
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Corresponding author

Correspondence to Sandra Kalil Bussadori.

Ethics declarations

This study received approval from the Human Research Ethics Committee of the university under protocol CAAE: 56952716.2.0000.5511. All participants or their legal guardians received clarifications regarding the objectives and procedures of the study and those agreeing to participate signed a statement of informed consent.

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The authors declare that they have no conflicts of interest.

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da Silva, F.C., Silva, T., Gomes, A.O. et al. Sensory and motor responses after photobiomodulation associated with physiotherapy in patients with incomplete spinal cord injury: clinical, randomized trial. Lasers Med Sci 35, 1751–1758 (2020). https://doi.org/10.1007/s10103-020-02968-6

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  • DOI: https://doi.org/10.1007/s10103-020-02968-6

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