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Comparison of long-pulsed Nd: YAG laser with cryotherapy in treatment of acral warts

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Abstract

Acral warts are considered as prevalent reasons for dermatologic consultations and remain an important continuing challenge until now because there is no consensus about optimal therapeutic modality. This study investigated the efficacy of long-pulsed Nd: YAG laser therapy and cryotherapy in treatment of acral warts. Patients who underwent treatment with cryotherapy or long-pulsed Nd: YAG laser therapy for symmetrical and bilateral warts on the extremities (hand and foot) that is confirmed by an expert dermatologist from May 2016 until March 2018 were assessed for enrollment in our study. Laser and cryotherapy sessions were applied every 2 weeks for a maximum of six sessions. Patients followed up and evaluated 3 months after the last treatment. Data were analyzed by SPSS (v.21. IBM Inc. IL). The P value less than 0.05 was considered significant. From 60 enrolled patients, 134 lesions were treated using cryotherapy and 114 other lesions treated with laser beam. Thirty-four males (average age 26.85 ± 7.528 years) and 26 females (average age 26.73 ± 5.640 years) participated. Finally, it was a significant reduction in both lesion width (P = 0.000) and length (P = 0.000) after the sessions of cryotherapy. The width and length of lesions is reduced significantly after each session of laser therapy similarly (P = 0.000). Cryotherapy and long-pulsed Nd: YAG laser are effective on the reduction of both width and length of lesions. Clinically, the methods are not different in their ultimate effects.

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References

  1. Viennet C, Gheit T, Muret P et al (2013) Assessment of the efficacy of a new formulation for plantar wart mummification: new experimental design and human papillomavirus identification. Clin Exp Dermatol 38:85–88

    Article  PubMed  CAS  Google Scholar 

  2. Lee DY, Park JH, Lee JH, Yang JM, Lee ES (2009) The use of dermoscopy for the diagnosis of plantar wart. J Eur Acad Dermatol Venereol 23:726–727

    Article  PubMed  Google Scholar 

  3. Bae JM, Kang H, Kim HO, Park YM (2009) Differential diagnosis of plantar wart from corn, callus and healed wart with the aid of dermoscopy. Br J Dermatol 160:220–222

    Article  PubMed  CAS  Google Scholar 

  4. Bacelieri R, Johnson SM (2005) Cutaneous warts: an evidence-based approach to therapy. Am Fam Physician 72:647–652

    PubMed  Google Scholar 

  5. Vlahovic TC, Khan MT (2016) The human papillomavirus and its role in plantar warts: a comprehensive review of diagnosis and management. Clin Podiatr Med Surg 33:337–353

    Article  PubMed  Google Scholar 

  6. Kwok CS, Gibbs S, Bennett C et al (2012) Topical treatments for cutaneous warts. Cochrane Database Syst Rev 9:CD001781

    Google Scholar 

  7. Mulhem E, Pinelis S (2011) Treatment of nongenital cutaneous warts. Am Fam Physician 84:288–293

    PubMed  Google Scholar 

  8. Wollina U (2003) Er:YAG laser followed by topical podophyllotoxin for hard-to-treat acral warts. J Cosmet Laser Ther 5:35–37

    Article  PubMed  Google Scholar 

  9. Han TY, Lee JH, Lee CK, Ahn JY, Seo SJ, Hong CK (2009) Long pulsed Nd:YAG laser treatment of warts: report on a series of 369 cases. J Korean Med Sci 24:889–893

    Article  PubMed  PubMed Central  Google Scholar 

  10. Park HS, Choi WS (2008) Pulsed dye laser treatment for viral warts: a study of 120 patients. J Dermatol 35:491–498

    Article  PubMed  Google Scholar 

  11. Padilla España L, Del Boz J, Fernández Morano T, Arenas Villafranca J, de Troya Martín M (2014) Topical cidofovir for plantar warts. Dermatol Ther 27:89–93

    Article  PubMed  Google Scholar 

  12. Gibbs S, Harvey I (2006) Topical treatments for cutaneous warts. Cochrane Database Syst Rev 3:CD001781

    Google Scholar 

  13. Kwok CS, Holland R, Gibbs S (2011) Efficacy of topical treatments for cutaneous warts: a meta-analysis and pooled analysis of randomized controlled trials. Br J Dermatol 165:233–246

    Article  PubMed  CAS  Google Scholar 

  14. Thomas KS, Keogh-Brown MR, Chalmers JR et al (2006) Effectiveness and cost effectiveness of salicylic acid and cryotherapy for cutaneous warts. An economic decision model. Health Technol Asses 10:iii ix-87

    Article  CAS  Google Scholar 

  15. El-Mohamady A-S, Mearag I, El-Khalawany M, Elshahed A, Shokeir H, Mahmoud A (2014) Pulsed dye laser versus long pulsed Nd:Yag laser in the treatment of plantar warts: a comparative study. Lasers Med Sci 29:1111–1116

    Article  Google Scholar 

  16. Cockayne S, Hewitt C, Hicks K et al (2011) Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial. BMJ 342:d3271

    Article  PubMed  PubMed Central  Google Scholar 

  17. El-Tonsy MH, Anbar TE, El-Domyati M, Barakat M (1999) Density of viral particles in pre and post long pulsed Nd: YAG laser hyperthermia therapy and cryotherapy in plantar warts. Int J Dermatol 38:393–398

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    M. Gheisari, B. Iranmanesh, N. Najar Nobari & M. Amani

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  1. M. Gheisari
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  2. B. Iranmanesh
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  3. N. Najar Nobari
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  4. M. Amani
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Correspondence to N. Najar Nobari.

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The authors declare that they have no conflict of interest.

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Reviewed and approved by Shahid Beheshti University of Medical Sciences IRIB; approval #IRCT 2016050127707 N1.

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Gheisari, M., Iranmanesh, B., Nobari, N.N. et al. Comparison of long-pulsed Nd: YAG laser with cryotherapy in treatment of acral warts. Lasers Med Sci 34, 397–403 (2019). https://doi.org/10.1007/s10103-018-2613-7

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  • DOI: https://doi.org/10.1007/s10103-018-2613-7

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