Skip to main content
SpringerLink
Log in

Laser-assisted hatching of human embryos: may two alternative approaches (thinning versus drilling) impact on implant rate?

  • Brief Report
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Van Duin M, Polman JE, De Breet IT et al (1994) Recombinant human zona pellucida protein ZP3 produced by chinese hamster ovary cells induces the human sperm acrosome reaction and promotes sperm-egg fusion. Biol Reprod 51:607–617

    Article  CAS  PubMed  Google Scholar 

  2. Trounson AO, Moore NW (1974) The survival and development of sheep eggs following complete or partial removal of the zona pellucida. J Reprod Fertil 41:97–105

    Article  CAS  PubMed  Google Scholar 

  3. Cohen J (1991) Assisted hatching of human embryos. J Vitro Fertil Embryo Transf IVF 8:179–190

    Article  CAS  Google Scholar 

  4. Wright G, Wiker S, Elsner C et al (1990) Observations on the morphology of pronuclei and nucleoli in human zygotes and implications for cryopreservation. Hum Reprod Oxf Engl 5:109–115

    Article  CAS  Google Scholar 

  5. Chan PJ (1987) Developmental potential of human oocytes according to zona pellucida thickness. J Vitro Fertil Embryo Transf IVF 4:237–241

    Article  CAS  Google Scholar 

  6. Cohen J, Elsner C, Kort H et al (1990) Impairment of the hatching process following IVF in the human and improvement of implantation by assisting hatching using micromanipulation. Hum Reprod Oxf Engl 5:7–13

    Article  CAS  Google Scholar 

  7. DeMeestere I, Barlow P, Leroy F (1997) Hardening of zona pellucida of mouse oocytes and embryos in vivo and in vitro. Int J Fertil Womens Med 42:219–222

    CAS  PubMed  Google Scholar 

  8. Tucker MJ, Morton PC, Wright G et al (1996) Enhancement of outcome from intracytoplasmic sperm injection: does co-culture or assisted hatching improve implantation rates? Hum Reprod Oxf Engl 11:2434–2437

    Article  CAS  Google Scholar 

  9. Dokras A, Sargent IL, Ross C et al (1991) The human blastocyst: morphology and human chorionic gonadotrophin secretion in vitro. Hum Reprod Oxf Engl 6:1143–1151

    Article  CAS  Google Scholar 

  10. Hershlag A, Feng HL (2005) Effect of prefreeze assisted hatching on postthaw survival of mouse embryos. Fertil Steril 84:1752–1754. doi:10.1016/j.fertnstert.2005.05.065

    Article  PubMed  Google Scholar 

  11. Jones AE, Wright G, Kort HI et al (2006) Comparison of laser-assisted hatching and acidified Tyrode’s hatching by evaluation of blastocyst development rates in sibling embryos: a prospective randomized trial. Fertil Steril 85:487–491. doi:10.1016/j.fertnstert.2005.07.1314

    Article  PubMed  Google Scholar 

  12. Mantoudis E, Podsiadly BT, Gorgy A et al (2001) A comparison between quarter, partial and total laser assisted hatching in selected infertility patients. Hum Reprod Oxf Engl 16:2182–2186

    Article  CAS  Google Scholar 

  13. World Health Organization (2010) WHO laboratory manual for the examination and processing of human semen, 5th edn. World Health Organization, Geneva

    Google Scholar 

  14. Luke B, Brown MB, Wantman E, Stern JE (2014) Factors associated with monozygosity in assisted reproductive technology pregnancies and the risk of recurrence using linked cycles. Fertil Steril 101:683–689. doi:10.1016/j.fertnstert.2013.11.034

    Article  PubMed  PubMed Central  Google Scholar 

  15. Alikani M, Noyes N, Cohen J, Rosenwaks Z (1994) Monozygotic twinning in the human is associated with the zona pellucida architecture. Hum Reprod Oxf Engl 9:1318–1321

    Article  CAS  Google Scholar 

  16. Blake DA, Forsberg AS, Johansson BR, Wikland M (2001) Laser zona pellucida thinning—an alternative approach to assisted hatching. Hum Reprod Oxf Engl 16:1959–1964

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Prenatal Diagnosis, Altamedica, Fetal-Maternal Medical Centre, Rome, Italy

    Francesco Padula & Claudio Giorlandino

  2. Department of Obstetrics and Gynaecology, Campus Bio Medico University, Via Alvaro del Portillo, 200, 00128, Rome, Italy

    Stella Capriglione

  3. Department of Reproductive Medicine, Altamedica, Fetal-Maternal Medical Centre, Rome, Italy

    Paola Iaconianni, Simona Gatti, Assunta Lippa & Salvatrice Elisa Minutolo

  4. Scientific Direction, Biostatistical Unit, Regina Elena National Cancer Institute, Rome, Italy

    Diana Giannarelli

Authors
  1. Francesco Padula
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Stella Capriglione
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Paola Iaconianni
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Simona Gatti
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Assunta Lippa
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Salvatrice Elisa Minutolo
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Diana Giannarelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Claudio Giorlandino
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Stella Capriglione.

Ethics declarations

The local Institutional Review Board approved the study.

Conflict of interest

The authors declare that they have no conflict of interest.

Funding

There is no funding source.

Ethical approval

This article does not contain any studies with human partecipants or animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Padula, F., Capriglione, S., Iaconianni, P. et al. Laser-assisted hatching of human embryos: may two alternative approaches (thinning versus drilling) impact on implant rate?. Lasers Med Sci 32, 1663–1666 (2017). https://doi.org/10.1007/s10103-017-2242-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10103-017-2242-6

Search

Navigation