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In vitro biological outcome of laser application for modification or processing of titanium dental implants

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Abstract

There are numerous functions for laser in modern implant dentistry including surface treatment, surface coating, and implant manufacturing. As laser application may potentially improve osseointegration of dental implants, we systematically reviewed the literature for in vitro biological responses to laser-modified or processed titanium dental implants. The literature was searched in PubMed, ISI Web, and Scopus, using keywords “titanium dental implants,” “laser,” “biocompatibility,” and their synonyms. After screening the 136 references obtained, 28 articles met the inclusion criteria. We found that Nd:YAG laser was the most commonly used lasers in the treatment or processing of titanium dental implants. Most of the experiments used cell attachment and cell proliferation to investigate bioresponses of the implants. The most commonly used cells in these assays were osteoblast-like cells. Only one study was conducted in stem cells. These in vitro studies reported higher biocompatibility in laser-modified titanium implants. It seems that laser radiation plays a vital role in cell response to dental implants; however, it is necessary to accomplish more studies using different laser types and parameters on various cells to offer a more conclusive result.

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Acknowledgments

This study was supported by a grant from Iran National Science Foundation (Project no. 95819948).

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Authors and Affiliations

  1. Department of Dental Biomaterials, School of Dentistry, Shahid Beheshti University of Medical Sciences, Evin, Tehran, 1983963113, Iran

    Ahmed Hindy & Fahimeh sadat Tabatabaei

  2. Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran

    Farzam Farahmand

  3. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Fahimeh sadat Tabatabaei

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Hindy, A., Farahmand, F. & Tabatabaei, F.s. In vitro biological outcome of laser application for modification or processing of titanium dental implants. Lasers Med Sci 32, 1197–1206 (2017). https://doi.org/10.1007/s10103-017-2217-7

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