Lasers in Medical Science

, Volume 31, Issue 4, pp 713–719 | Cite as

Effect of low-level laser therapy on tooth sensitivity induced by in-office bleaching

  • Horieh Moosavi
  • Nooshin Arjmand
  • Farzaneh AhrariEmail author
  • Majid Zakeri
  • Fatemeh Maleknejad
Original Article


This study aimed to investigate the effect of low-level laser therapy (LLLT) on tooth sensitivity induced by in-office bleaching. Sixty-six patients enrolled in this randomized clinical trial. Following the in-office procedure with 40 % hydrogen peroxide, the participants were randomly divided into three groups. The patients in group 1 received irradiation from a low-level red laser (LLRL; 660 nm, 200 mW, 15 s, 12 J/cm2), whereas participants in group 2 were subjected to a low-level infrared laser (LLIL; 810 nm) under similar conditions as in group 1. In group 3 (placebo), the laser treatment was the same as that in groups 1 and 2, but without energy output. The degree of tooth sensitivity was recorded at 1, 24, and 48 h after bleaching using a visual analog scale (VAS). The change in tooth shade was measured 30 days after tooth whitening. The intensity of tooth sensitivity was not significantly different between groups at 1 h after bleaching (p > 0.05). At 24 h after therapy, pain level was significantly lower in the LLIL group compared to the LLRL and placebo groups (p < 0.05). At 48 h after bleaching, VAS scores in the LLIL and LLRL groups were comparable to each other (p > 0.05) and both were significantly lower than that of the placebo group (p < 0.05). There was no significant difference in the efficacy of tooth whitening among groups (p > 0.05). LLLT with an infrared diode laser could be recommended as a suitable strategy to reduce the intensity of tooth sensitivity after in-office bleaching.


Bleaching Hydrogen peroxide Tooth sensitivity Low-level laser Low-power laser Therapy In-office bleaching Pain 



The authors would like to thank the vice-chancellor for research of Mashhad University of Medical Sciences for the financial support of this project (grant number 921922). The results presented in this paper have been taken from a post-graduate student thesis (thesis number 536).

Compliance with ethical standards

The research protocol was reviewed and approved by the ethics committee of Mashhad University of Medical Sciences, and it was registered in the Iranian Registry of Clinical Trials (IRCT registration number: IRCT201408131509N2). The study was performed in accordance with the CONSORT statement.


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Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  • Horieh Moosavi
    • 1
  • Nooshin Arjmand
    • 2
  • Farzaneh Ahrari
    • 3
    Email author
  • Majid Zakeri
    • 4
  • Fatemeh Maleknejad
    • 3
  1. 1.Dental Materials Research Center, School of DentistryMashhad University of Medical SciencesMashhadIran
  2. 2.School of DentistryMashhad University of Medical SciencesMashhadIran
  3. 3.Dental Research Center, School of DentistryMashhad University of Medical SciencesMashhadIran
  4. 4.Private PracticeMashhadIran

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