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Is there a protocol in experimental skin wounds in rats using low-level diode laser therapy (LLDLT) combining or not red and infrared wavelengths? Systematic review

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Abstract

A systematic review addressing experiments with healing of skin wounds in rats using LLDLT with different active means seeking to identify a pattern in adjustments such as laser wavelength, power and fluency and analysing wound healing parameters, such as wound area, presence of fibroblasts, angiogenesis, leukocyte infiltration, epithelial coverage and antibacterial effect. It was perceived that a protocol does not exist in view of the wide variation in the use of power (9 to 500 mW) and fluency (1 to 60 J/cm2); however, between the different wavelengths, the highlight was the combined use of red and infrared wavelengths showing better results than when used alone.

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Authors and Affiliations

  1. Campus A.C. Simões–ICBS-UFAL, Anatomia Humana da Universidade Federal de Alagoas, Av. Lourival Melo Mota, s/n Tabuleiro dos Martins, CEP 57072-900, Maceió, AL, Brazil

    Fernando José Camello de Lima, Olavo Barbosa de Oliveira Neto & Fernando Wagner Silva Ramos

  2. Campus A.C. Simões–ICBS-UFAL, Faculdade de Medicina da Universidade Federal de Alagoas, Av. Lourival Melo Mota, s/n Tabuleiro dos Martins, CEP 57072-900, Maceió, AL, Brazil

    Fabiano Timbó Barbosa

  3. Campus A.C. Simões–ICBS-UFAL, Ciências da Saúde na Universidade Federal de Alagoas, Av. Lourival Melo Mota, s/n Tabuleiro dos Martins, CEP 57072-900, Maceió, AL, Brazil

    Ailton Mota do Nascimento Galvão

  4. Médica da Universidade de Ciências da Saúde de Alagoas, Rua Jorge de Lima, 113, Trapiche da Barra, Maceió, AL, Brazil

    Christiane Calheiros Farias de Lima

  5. Anatomia Humana da Universidade Federal de Alagoas, Av. Lourival Melo Mota, s/n Tabuleiro dos Martins, CEP 57072-900, Maceió, AL, Brazil

    Célio Fernando de Sousa Rodrigues

Authors
  1. Fernando José Camello de Lima
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  2. Olavo Barbosa de Oliveira Neto
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  3. Fabiano Timbó Barbosa
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  4. Ailton Mota do Nascimento Galvão
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  5. Fernando Wagner Silva Ramos
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  6. Christiane Calheiros Farias de Lima
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  7. Célio Fernando de Sousa Rodrigues
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Correspondence to Fernando José Camello de Lima.

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de Lima, F.J.C., de Oliveira Neto, O.B., Barbosa, F.T. et al. Is there a protocol in experimental skin wounds in rats using low-level diode laser therapy (LLDLT) combining or not red and infrared wavelengths? Systematic review. Lasers Med Sci 31, 779–787 (2016). https://doi.org/10.1007/s10103-016-1893-z

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  • DOI: https://doi.org/10.1007/s10103-016-1893-z

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