Skip to main content

Advertisement

SpringerLink
Log in

The effects of LED emissions on sternotomy incision repair after myocardial revascularization: a randomized double-blind study with follow-up

  • Original Article
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript

Abstract

This study aimed to analyze the effects of light-emitting diode (LED) therapy on sternotomy pain and healing in patients who underwent coronary artery bypass grafting (CABG). The patients were followed for 6 months after the surgery to determine their dehiscence. This study was conducted with 90 volunteers who electively submitted to CABG. The volunteers were randomly allocated into three different groups of equal size: LED (λ of 640 ± 20 nm and spatial average energy fluency of 1.2 J/cm2 during hospitalization), placebo, or control. The outcomes assessed were pain when coughing by a visual analog scale (VAS) and the McGill questionnaire and sternotomy healing by clinical assessment and photographical register end interpretation. The LED group had better pain reduction, as indicated by both the VAS and the McGill questionnaire (number of words chosen and pain index) (p ≤ 0.05), on days 6 and 8 after hospital discharge compared to the placebo and control groups. One month after surgery, almost no individual mentioned pain when coughing. Three researchers blindly analyzed the incision photographs to determine hyperemia and wound closure, and they found that the LED group had both less hyperemia and less incision bleeding or dehiscence. The LED therapy (640 nm) had an analgesic effect on the sternotomies of patients who underwent CABG, increasing their incision healing and preventing dehiscence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Piegas LS, Bittar OJNV, Haddad N (2009) Review article myocardial revascularization surgery (MRS). Results from National Health System (SUS). Arq Bras Cardiol 93:513–518

    Article  Google Scholar 

  2. Ghali W a, Quan H, Brant R (1998) Coronary artery bypass grafting in Canada: hospital mortality rates, 1992–1995. CMAJ 159:926–930

    CAS  PubMed Central  PubMed  Google Scholar 

  3. Bukkapatnam RN, Yeo KK, Li Z, Amsterdam E a (2010) Operative mortality in women and men undergoing coronary artery bypass grafting (from the California Coronary Artery Bypass Grafting Outcomes Reporting Program). Am J Cardiol 105:339–342. doi:10.1016/j.amjcard.2009.09.035

    Article  PubMed  Google Scholar 

  4. El Oakley RM, Wright JE (1996) Postoperative mediastinitis: classification and management. Ann Thorac Surg 61:1030–1036. doi:10.1016/0003-4975(95)01035-1

    Article  PubMed  Google Scholar 

  5. Xavier M, David DR, de Souza RA et al (2010) Anti-inflammatory effects of low-level light emitting diode therapy on Achilles tendinitis in rats. Lasers Surg Med 42:553–558. doi:10.1002/lsm.20896

    Article  PubMed  Google Scholar 

  6. Casalechi HL, Nicolau R a, Casalechi VL et al (2009) The effects of low-level light emitting diode on the repair process of Achilles tendon therapy in rats. Lasers Med Sci 24:659–665. doi:10.1007/s10103-008-0607-6

    Article  PubMed  Google Scholar 

  7. Oliveira RA, Matos AF, Regina N et al (2013) Low-intensity laser therapy and led (light emitting diode) therapy in mechanical resistance of Rattus norvegicus chest incision with implant of steel wire for sternal suture. Braz J Biomed Eng 29:166–174. doi:10.4322/rbeb.2013.016

    Google Scholar 

  8. Whelan HT, Buchmann EV, Dhokalia A et al (2003) Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. J Clin Laser Med Surg 21:67–74. doi:10.1089/104454703765035484

    Article  PubMed  Google Scholar 

  9. Dall Agnol MA, Nicolau RA, de Lima CJ, Munin E (2009) Comparative analysis of coherent light action (laser) versus non-coherent light (light-emitting diode) for tissue repair in diabetic rats. Lasers Med Sci 24:909–916. doi:10.1007/s10103-009-0648-5

    Article  PubMed  Google Scholar 

  10. de Morais NCR, Barbosa AM, Vale ML et al (2010) Anti-inflammatory effect of low-level laser and light-emitting diode in zymosan-induced arthritis. Photomed Laser Surg 28:227–232

    Article  PubMed  Google Scholar 

  11. Bastos JLN, Lizarelli RFZ, Parizotto N a (2009) Comparative study of laser and LED systems of low intensity applied to tendon healing. Laser Phys 19:1925–1931. doi:10.1134/S1054660X09170022

    Article  CAS  Google Scholar 

  12. Melzack R (1975) The McGill pain questionnaire: major properties and score methods. Pain 1:277–299

    Article  CAS  PubMed  Google Scholar 

  13. Menezes Costa LDC, Maher CG, McAuley JH et al (2011) The Brazilian-Portuguese versions of the McGill Pain Questionnaire were reproducible, valid, and responsive in patients with musculoskeletal pain. J Clin Epidemiol 64:903–912. doi:10.1016/j.jclinepi.2010.12.009

    Article  Google Scholar 

  14. Bassalobre J, Borges C, Leandra D et al (2006) Pain intensity and postoperative functional assessment after heart surgery. Braz J Cardiovasc Surg 21:393–402

    Google Scholar 

  15. Piva JAAC, Silva VS, Abreu EMC, Nicolau RA (2011) Effect of low-level laser therapy on the initial stages of. Braz An Dermatol 86:947–954

    Google Scholar 

  16. Sakurai Y, Yamaguchi M, Abiko Y (2000) Inhibitory effect of low-level laser irradiation on LPS-stimulated prostaglandin E2 production and cyclooxygenase-2 in human gingival fibroblasts. Eur J Oral Sci 108:29–34

    Article  CAS  PubMed  Google Scholar 

  17. Nomura K, Yamaguchi M, Abiko Y (2001) Inhibition of interleukin-1β production and gene expression in human gingival fibroblasts by low-energy laser irradiation. Lasers Med Sci 16:218–223. doi:10.1007/PL00011358

    Article  CAS  PubMed  Google Scholar 

  18. Bjordal JM, Johnson MI, Iversen V et al (2006) Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg 24:158–168. doi:10.1089/pho.2006.24.158

    Article  CAS  PubMed  Google Scholar 

  19. Dargaville TR, Farrugia BL, Broadbent J a et al (2013) Sensors and imaging for wound healing: a review. Biosens Bioelectron 41:30–42. doi:10.1016/j.bios.2012.09.029

    Article  CAS  PubMed  Google Scholar 

  20. Terris DD, Woo C, Jarczok MN, Ho CH (2011) Comparison of in-person and digital photograph assessment of stage III and IV pressure ulcers among veterans with spinal cord injuries. J Rehabil Res Dev 48:215. doi:10.1682/JRRD.2010.03.0036

    Article  PubMed  Google Scholar 

  21. Olbrecht V a, Barreiro CJ, Bonde PN et al (2006) Clinical outcomes of noninfectious sternal dehiscence after median sternotomy. Ann Thorac Surg 82:902–907. doi:10.1016/j.athoracsur.2006.04.058

    Article  PubMed  Google Scholar 

  22. Tuyl LJ, Mackney JH, Johnston CL (2012) Management of sternal precautions following median sternotomy by physical therapists in Australia: a web-based survey. Phys Ther 92:83–97. doi:10.2522/ptj.20100373

    Article  PubMed  Google Scholar 

  23. Huang P-J, Huang Y-C, Su M-F et al (2007) In vitro observations on the influence of copper peptide aids for the LED photoirradiation of fibroblast collagen synthesis. Photomed Laser Surg 25:183–190. doi:10.1089/pho.2007.2062

    Article  CAS  PubMed  Google Scholar 

  24. Caetano KS, Frade MAC, Minatel DG et al (2009) Phototherapy improves healing of chronic venous ulcers. Photomed Laser Surg 27:111–118. doi:10.1089/pho.2008.2398

    Article  PubMed  Google Scholar 

  25. De Sousa APC, Santos JN, Dos Reis J a et al (2010) Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model. Photomed Laser Surg 28:547–552. doi:10.1089/pho.2009.2605

    Article  PubMed  Google Scholar 

  26. Holder MJ, Milward MR, Palin WM et al (2012) Effects of red light-emitting diode irradiation on dental pulp cells. J Dent Res 91:961–966. doi:10.1177/0022034512456040

    Article  CAS  PubMed  Google Scholar 

  27. Neves SMV, Nicolau RA, Filho ALMM et al (2013) Digital photogrammetry and histomorphometric assessment of the effect of non-coherent light (light-emitting diode) therapy (λ640 ± 20 nm) on the repair of third-degree burns in rats. Lasers Med Sci. doi:10.1007/s10103-013-1312-7

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Lasertherapy and Photobiology Center, Research and Development Institute (IP&D), Universidade do Vale do Paraíba (UNIVAP), São Paulo, Brazil

    Rauirys Alencar de Oliveira & Renata Amadei Nicolau

  2. Novafapi College, Teresina, Piauí, Brazil

    Rauirys Alencar de Oliveira & Gilderlene Alves Fernandes

  3. University of Piauí State (UESPI), Teresina, Piauí, Brazil

    Andréa Conceição Gomes Lima

  4. Cardiac Surgery Department, Santa Maria Hospital, Teresina, Piauí, Brazil

    Antônio Dib Tajra Filho & Raimundo de Barros Araújo Jr.

Authors
  1. Rauirys Alencar de Oliveira
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gilderlene Alves Fernandes
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Andréa Conceição Gomes Lima
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Antônio Dib Tajra Filho
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Raimundo de Barros Araújo Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Renata Amadei Nicolau
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rauirys Alencar de Oliveira.

Rights and permissions

Reprints and permissions

About this article

Cite this article

de Oliveira, R.A., Fernandes, G.A., Lima, A.C.G. et al. The effects of LED emissions on sternotomy incision repair after myocardial revascularization: a randomized double-blind study with follow-up. Lasers Med Sci 29, 1195–1202 (2014). https://doi.org/10.1007/s10103-013-1503-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10103-013-1503-2

Keywords

Search

Navigation