Abstract
The aim of this study was to compare low-level laser therapy (LLLT) as adjuvant treatment for induced periodontitis with scaling and root planing (SRP) in dexamethasone-treated rats. One-hundred twenty rats were divided into groups: D group (n = 60), treated with dexamethasone; ND group (n = 60) treated with saline solution. In both groups, periodontal disease was induced by ligature at the left first mandibular molar. After 7 days, the ligature was removed and all animals were subjected to SRP and were divided according to the following treatments: SRP, irrigation with saline solution (SS); SRP + LLLT, SS and laser irradiation (660 nm; 24 J; 0.428 W/cm2). Ten animals in each treatment were killed after 7 days, 15 days and 30 days. The radiographic and histometric values were statistically analyzed. In all groups radiographic and histometric analysis showed less bone loss (P < 0.05) in animals treated with SRP + LLLT in all experimental periods. SRP + LLLT was an effective adjuvant conventional treatment for periodontitis in rats treated with dexamethasone.
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Acknowledgments
This work is attributed to the Department of Periodontology, Araçatuba Dental School, State University of São Paulo (UNESP) Araçatuba, São Paulo, Brazil. This study was financially supported by CAPES (Coordination for the Improvement of Higher Education Personnel; Brasilia, DF, Brazil) and CNPq (National Council for Scientific and Technological Development; Brasilia, DF, Brazil). The authors would also like to thank Bruno Theodoro Luciano from the Institute of International Relations of the University of Brasilia, for the English review.
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Garcia, V.G., Fernandes, L.A., de Almeida, J.M. et al. Comparison between laser therapy and non-surgical therapy for periodontitis in rats treated with dexamethasone. Lasers Med Sci 25, 197–206 (2010). https://doi.org/10.1007/s10103-009-0678-z
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DOI: https://doi.org/10.1007/s10103-009-0678-z