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Light sources for photodynamic inactivation of bacteria

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Bacteria have an important role in human and animal morbidity, and a great number of them have developed antibiotic resistance. In the past recent years a new way of dealing with this problem has been studied: photodynamic inactivation. This method is based on administration of a photosensitizing substance that fixes itself in the bacterial cell followed by exposure to a light source. In the experiments done by many researchers on photodynamic inactivation of bacteria, both coherent and non-coherent light sources were used. This article is a review of these light sources and of some experimental results obtained by different authors.

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This work was financed by the Ministry of Education and Research by CEEX Programme no. 113/2006.

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Correspondence to Mihaela Antonina Calin.

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Calin, M.A., Parasca, S.V. Light sources for photodynamic inactivation of bacteria. Lasers Med Sci 24, 453–460 (2009).

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