Skip to main content
Log in

Intense pulsed light photoepilation in hirsute women: the role of obesity

  • Original Article
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript

Abstract

Intense pulsed light (IPL) has shown diverse results in hair clearance related to treatment protocols or skin phototype. Hirsutism may be due to endocrine disease, as in polycystic ovary syndrome (PCOS) and congenital adrenal hyperplasia (CAH), both of which conditions may be associated with obesity. Obesity complicates the metabolic pattern, particularly in terms of insulin resistance, which may worsen the clinical condition of hirsutism. This study evaluated the role of obesity in photoepilation, comparing the clinical efficacy, long-term hair reduction and patient satisfaction in 40 hirsute women with PCOS or CAH, either obese (n = 20) or of normal weight (n = 20). The IPL settings were the same for both groups, but the number of sessions varied according to the clinical results. Obese patients showed a statistically significant severity of initial hirsutism if compared to the non-obese population and, for this reason, required more sessions to achieve hair reduction. The results were maintained at the 2-year follow-up examination, with a high satisfaction rate in both groups.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Haedersdal M, Wulf HC (2006) Evidence based review of hair removal using lasers and light sources. J Eur Acad Dermatol Venereol 20:9–20. doi:10.1111/j.1468-3083.2005.01327.x

    Article  CAS  PubMed  Google Scholar 

  2. Troilius A, Troilius C (1999) Hair removal with a second generation broad spectrum intense pulsed light source—a long term follow up. J Cutan Laser Ther 1:173–178. doi:10.1080/14628839950516832

    Article  CAS  PubMed  Google Scholar 

  3. Fodor L, Menachem M, Ramon Y, Shoshani O, Rissin Y, Eldor L, Egozi D, Peled IJ, Ullmann Y (2005) Hair removal using intense pulsed light (Epilight): patient satisfaction, our experience, and literature review. Ann Plast Surg 54:8–14. doi:10.1097/01.sap.0000141940.34379.78

    Article  CAS  PubMed  Google Scholar 

  4. Sadick NS, Weiss RA, Shea CR, Nagel H, Nicholson J, Prieto VG (2000) Long term photoepilation using a broad spectrum intense pulsed light source. Arch Dermatol 136:1336–1340. doi:10.1001/archderm.136.11.1336

    Article  CAS  PubMed  Google Scholar 

  5. El Bedewi AF (2004) Hair removal with intense pulsed light. Laser Med Sci 19:51

    Article  Google Scholar 

  6. Moreno-Arias G, Castelo-Branco C, Ferrando J (2002) Paradoxical effect after IPL photoepilation. Dermatol Surg 28:1013–1016. doi:10.1046/j.1524-4725.2002.02101.x

    PubMed  Google Scholar 

  7. Griffing GT (2006) Hirsutism, in emedicine.com, May 12

  8. Rosenfield RL (2005) Hirsutism. N Engl J Med 353:2578–2588. doi:10.1056/NEJMcp033496

    Article  CAS  PubMed  Google Scholar 

  9. World Health Organization (WHO) (2000) Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 894:i–xii

  10. The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group (2004) Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 19:41–47

    Article  Google Scholar 

  11. Fitzpatrick TB (1988) The validity and practicality of sun reactive skin types I through VI. Arch Dermatol 124:869–871

    Article  CAS  PubMed  Google Scholar 

  12. Ferriman D, Gallwey JD (1961) Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 21:1440–1447

    Article  CAS  PubMed  Google Scholar 

  13. Schroeter CA, Groenewegen JS, Reineke T, Neumann HAM (2004) Hair reduction using intense pulsed light source. Dermatol Surg 30:168–173. doi:10.1111/j.1524-4725.2004.30054.x

    PubMed  Google Scholar 

  14. Philpott MP, Sanders DA, Kealey T (1994) Effects of insulin and insulin-like growth factors on cultured human hair follicles: IGF-I at physiologic concentrations is an important regulator of hair follicle growth in vitro. J Invest Dermatol 102:857–861. doi:10.1111/1523-1747.ep12382494

    Article  CAS  PubMed  Google Scholar 

  15. Humbel RE (1990) Insulin like growth factors I and II. Eur J Biochem 190:445–462. doi:10.1111/j.1432-1033.1990.tb15595.x

    Article  CAS  PubMed  Google Scholar 

  16. Daughaday WH (1990) The possible autocrine/paracrine and endocrine roles of insulin like growth factors of human tissues. Endocrinol 127:1–4

    Article  CAS  Google Scholar 

  17. Rosenfield RL, Moll GW Jr (1983) The role of proteins in the distribution of plasma androgens and estradiol. In: Molinatti GM, Martini L, James VHT (eds) Androgenization in women: pathophysiology and clinical concepts. Raven Press, New York, pp 25–45

    Google Scholar 

  18. Nestler JE, Powers LP, Matt DW et al (1991) A direct effect of hyperinsulinemia on serum sex-hormone binding globulin levels in obese women with the polycystic ovary syndrome. J Clin Endocrinol Metab 72:83–89

    Article  CAS  PubMed  Google Scholar 

  19. Toosi P, Sadinghha A, Sharifian A, Razavi GM (2006) A comparison study of the efficacy and side effects of different light sources in hair removal. Lasers Med Sci 21:1–4. doi:10.1007/s10103-006-0373-2

    Article  PubMed  Google Scholar 

  20. Clayton WJ, Lipton M, Elford J, Rustin M, Sherr L (2005) Randomized controlled trial of laser treatment among hirsute woman with polycystic ovary syndrome. Br J Dermatol 152:986–992. doi:10.1111/j.1365-2133.2005.06426.x

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Francesca R. Grippaudo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grippaudo, F.R., Angelini, M., Chiossi, M.R. et al. Intense pulsed light photoepilation in hirsute women: the role of obesity. Lasers Med Sci 24, 415–418 (2009). https://doi.org/10.1007/s10103-008-0583-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10103-008-0583-x

Keywords

Navigation