Abstract
Septic arthritis is a diagnostic emergency. The white blood cell (WBC) count, in synovial fluid (SF), can guide the diagnosis. From November 2021 to November 2022, we included 350 SF. The WBC count was performed with the Iris iQ® 200 compared with the manual method. Automated and manual counts displayed good correlation. However, a Bland Altman plot demonstrates a higher percentage difference at higher WBC counts. The use of Iris iQ® 200 for SF analysis enables a rapid and accurate assessment for WBC count. Its implementation would advantageously replace the long and tedious optical analysis in daily routine.
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Acknowledgements
We would like to thank the lab technicians for the SF collection and the medical residents for their contribution in this study.
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According to the French and European legislation, in this monocentric prospective study, the use of anonymized human samples from care and data by the practitioners does not need the approval of an ethics committee when the aim is to improve the practices of biology analysis. This study was recorded at Nantes University hospital by the local Data Privacy Officer under the reference TS005-BIO-AP-2019.
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Ruffier d’Epenoux, L., Fayoux, E., Bémer, P. et al. Development and evaluation of automated synovial fluid total cell count on an Iris iQ® 200 for identifying patients at risk of septic arthritis. Eur J Clin Microbiol Infect Dis 42, 1031–1036 (2023). https://doi.org/10.1007/s10096-023-04628-3
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DOI: https://doi.org/10.1007/s10096-023-04628-3