Abstract
The aim of this study was to determine the occurrence of urogenital mycoplasmas in urogenital tract of women with systemic lupus erythematosus (SLE). The study group included 36 women diagnosed with SLE and 100 healthy controls. Mycoplasmas were detected with microculture and PCR in 13/36 (36.1%) women with SLE and in 25/100 (25%) controls. In both groups, U. parvum occurred significantly more frequently. M. genitalium was detected in 3/36 (8.3%) SLE patients and in 3/100 (3%) controls. FVU as a material decreased the number of positive results from 33.3% to 30.6% compared with swabs.
Although the incidence of mycoplasmas in urogenital tract of women with SLE and controls did not differ statistically, it is important to consider them as a potential etiology of urogenital infection when clinical symptoms are present, but etiology is unknown or uncertain.
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This study was supported by the grant from the Medical University of Silesia (KNW-1-061/K/8/O).
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All procedures performed in studies involving human participants were approved by the local Bioethical Committee (KNW/0022/KB1/88/09) and in accordance with the 1964 Helsinki Declaration and its later amendments. All study subjects agreed to participate in the study and signed an informed consent form.
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Alicja, E., Małgorzata, R., Małgorzata, A. et al. Prevalence of urogenital mycoplasmas in women with systemic lupus erythematosus (SLE): preliminary study. Eur J Clin Microbiol Infect Dis 39, 717–721 (2020). https://doi.org/10.1007/s10096-019-03783-w
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DOI: https://doi.org/10.1007/s10096-019-03783-w