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Prevalence rates of six selected infectious diseases among African migrants and refugees: a systematic review and meta-analysis

  • A. Chernet
  • J. Utzinger
  • V. Sydow
  • N. Probst-Hensch
  • D. H. Paris
  • N. D. Labhardt
  • A. Neumayr
Review

Abstract

The objective of this paper was to systematically review the literature on the prevalence of selected infectious diseases among migrants/refugees of African origin and to provide policy makers and health care professionals with evidence-based information. We pursued a systematic review and meta-analysis to determine the prevalence of six selected infectious diseases (i.e., syphilis, helminthiasis, schistosomiasis, intestinal protozoa infections, hepatitis B, and hepatitis C) among migrants/refugees of African origin. Three electronic databases (i.e., PubMed, EMBASE, and ISI Web of Science) were searched without language restrictions. Relevant data were extracted and random-effects meta-analyses conducted. Only adjusted estimates were analyzed to help account for heterogeneity and potential confounding. We assessed the quality of evidence using the GRADE approach. The results were stratified by geographical region. Ninety-six studies were included. The evidence was of low quality due to the small numbers of countries, infectious diseases, and participants included. African migrants/refugees had median (with 95% confidence interval [95% CI]) prevalence for syphilis, helminthiasis, schistosomiasis, intestinal protozoa infection, hepatitis B, and hepatitis C of 6.0% [95% CI: 2.0–7.0%], 13.0% [95% CI: 9.5–14.5%], 14.0% [95% CI: 13.0–17.0%], 15.0% [95% CI: 10.5–21.0%], 10.0% [95% CI: 6.0–14.0%], and 3.0% [95% CI: 1.0–4.0%], respectively. We found high heterogeneity regardless of the disease (I 2; minimum 97.5%, maximum 99.7%). The relatively high prevalence of some infectious diseases among African migrants/refugees warrants for systematic screening. The large heterogeneity of the available published data does not allow for stratifying such screening programs according to the geographical origin of African migrants/refugees.

Notes

Funding

This study did not receive funds from any funding agents.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the Swiss Tropical and Public Health Institute institutional research commission.

Informed consent

As this research pertained to a systematic review and meta-analysis of published articles, there was no need to collect informed consent.

Supplementary material

10096_2017_3126_MOESM1_ESM.docx (105 kb)
ESM 1 (DOCX 105 kb)
10096_2017_3126_MOESM2_ESM.docx (108 kb)
ESM 2 (DOCX 107 kb)

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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • A. Chernet
    • 1
    • 2
  • J. Utzinger
    • 1
    • 2
  • V. Sydow
    • 1
    • 2
  • N. Probst-Hensch
    • 1
    • 2
  • D. H. Paris
    • 1
    • 2
  • N. D. Labhardt
    • 1
    • 2
    • 3
  • A. Neumayr
    • 1
    • 2
  1. 1.Swiss Tropical and Public Health InstituteBaselSwitzerland
  2. 2.University of BaselBaselSwitzerland
  3. 3.Division of Infectious Disease and Hospital EpidemiologyUniversity Hospital BaselBaselSwitzerland

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