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Clinical manifestation and prognostic factors of non-cholerae Vibrio infections

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European Journal of Clinical Microbiology & Infectious Diseases Aims and scope Submit manuscript

Abstract

Infections caused by non-cholerae Vibrio are uncommon. From July 2004 to June 2010, a total of 218 isolates of Vibrio species were identified from 171 patients treated at Chi Mei Medical Center, Taiwan. A total of 173 isolates of non-cholerae Vibrio species were isolated from 127 patients. The most common type of infection was acute gastroenteritis (59.8%), followed by skin and soft tissue infection (SSTI) (26.0%) and primary bacteremia (11.0%). Other types of infection included biliary tract infection, peritonitis, and acute otitis media, each at a rate of less than 2%. For patients with acute gastroenteritis, V. parahaemolyticus comprised 92.1% of cases, but V. vulnificus was the most common pathogen causing SSTI. All episodes of bacteremia were caused by V. vulnificus. The all-cause mortality rate was 18.8% of 32 patients with SSTI and the fatality rate was significantly higher among patients with decreased albumin, elevated lactate, use of mechanical ventilation, intensive care unit (ICU) admission, and the presence of shock. In conclusion, non-cholerae Vibrio species caused protean manifestations that vary with the infecting Vibrio species. This epidemiological study helps physicians to better understand the clinical characteristics of infections caused by different non-cholerae Vibrio species.

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Authors and Affiliations

  1. Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan

    C. C. Hou, C. C. Lai, W. L. Liu & C. M. Chao

  2. Department of Internal Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan

    Y. H. Chiu

  3. Department of Laboratory and Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

    P. R. Hsueh

Authors
  1. C. C. Hou
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  2. C. C. Lai
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  3. W. L. Liu
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  4. C. M. Chao
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  5. Y. H. Chiu
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  6. P. R. Hsueh
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Correspondence to P. R. Hsueh.

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Hou, C.C., Lai, C.C., Liu, W.L. et al. Clinical manifestation and prognostic factors of non-cholerae Vibrio infections. Eur J Clin Microbiol Infect Dis 30, 819–824 (2011). https://doi.org/10.1007/s10096-011-1162-9

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  • DOI: https://doi.org/10.1007/s10096-011-1162-9

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