Abstract
Staphylococcal scalded skin syndrome (SSSS) is the clinical term used to describe a range of blistering skin disorders induced by the exfoliative toxins of Staphylococcus aureus and prevalently affects neonates, infants and toddlers who lack antibodies to S. aureus toxins. SSSS is a highly contagious disease and is characterised by erythema and fever, followed by the formation of large fragile superficial blisters, which rupture only to leave extensive areas of denuded skin. A diagnosis of SSSS relies on the clinical picture, as well as on histological and microbiological findings. Neonates and young infants are particularly susceptible to a lack of the protective skin barrier, which may cause excessive protein and fluid losses, hypothermia and secondary infection. Due to a complete denudation of skin, the patients also suffer from almost unbearable pain. In our communication, we present an innovative temporary coverage of the denuded skin with Suprathel® (PolyMedics Innovations GmbH, Denkendorf, Germany). Suprathel® relieves pain, prevents heat loss and secondary infection, accelerates wound healing, does not need to be changed and makes daily care easy for the nurses and is well tolerable for the patient.
References
Ritter von Rittershain G (1878) Die exfoliative dermatitis jüngerer Säuglinge. Zent-Ztg Kinderheilkunde 2:3–23
Melish ME, Glasgow LA (1970) The staphylococcal scalded-skin syndrome: development of an experimental model. N Engl J Med 282:1114–1119
Nishifuji K, Sugai M, Amagai M (2008) Staphylococcal exfoliative toxins: “molecular scissors” of bacteria that attack the cutaneous defense barrier in mammals. J Dermatol Sci 49:21–31
Cribier B, Piemont Y, Grosshans E (1994) Staphylococcal scalded skin syndrome in adults. A clinical review illustrated with a new case. J Am Acad Dermatol 30:319–324
Murray RJ (2005) Recognition and management of Staphylococcus aureus toxin-mediated disease. Intern Med J 35(Suppl 2):S106–S119
Ladhani S, Joannou CL, Lochrie DP, Evans RW, Poston SM (1999) Clinical, microbial, and biochemical aspects of the exfoliative toxins causing staphylococcal scalded-skin syndrome. Clin Microbiol Rev 12(2):224–242
Sheridan RL, Briggs SE, Remensnyder JP, Gagnon SW, Doody DP, Ryan DP, Tompkins RG (1995) The burn unit as a resource for the management of acute nonburn conditions in children. J Burn Care Rehabil 16(1):62–64
Lowney ED, Baublis JV, Kreye GM, Harrell ER, McKenzie AR (1967) The scalded skin syndrome in small children. Arch Dermatol 95(4):359–369
Margileth AM (1975) Scalded skin syndrome: diagnosis, differential diagnosis, and management of 42 children. South Med J 68(4):447–454
Elias PM, Fritsch P, Epstein EH (1977) Staphylococcal scalded skin syndrome. Clinical features, pathogenesis, and recent microbiological and biochemical developments. Arch Dermatol 113(2):207–219
Simpson C (2003) The management of staphylococcal scalded skin syndrome in infants. Nurs Times 99(42):59–61
Patel GK (2004) Treatment of staphylococcal scalded skin syndrome. Expert Rev Anti Infect Ther 2(4):575–587
Blyth M, Estela C, Young AE (2008) Severe staphylococcal scalded skin syndrome in children. Burns 34(1):98–103
Uhlig C, Rapp M, Hartmann B, Hierlemann H, Planck H, Dittel KK (2007) Suprathel—an innovative, resorbable skin substitute for the treatment of burn victims. Burns 33(2):221–229
Schwarze H, Küntscher M, Uhlig C, Hierlemann H, Prantl L, Ottomann C, Hartmann B (2008) Suprathel, a new skin substitute, in the management of partial-thickness burn wounds: results of a clinical study. Ann Plast Surg 60(2):181–185
Conflict of interest
The authors indicate that they have no financial relationships to this article to disclose and they do not have any relationship to the manufacturer of the described dressing.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Mueller, E., Haim, M., Petnehazy, T. et al. An innovative local treatment for staphylococcal scalded skin syndrome. Eur J Clin Microbiol Infect Dis 29, 893–897 (2010). https://doi.org/10.1007/s10096-010-0927-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10096-010-0927-x