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Metabolic properties of lactobacilli in women experiencing recurring episodes of bacterial vaginosis with vaginal pH ≥ 5

Abstract

While 60% of women experiencing recurring episodes of bacterial vaginosis (BV) with vaginal pH ≥ 5 are depleted of resident probiotic lactobacilli, the remainder carry one or more strains of lactobacilli. Their ability to make D-lactic acid is, however, low (3.94 ± 0.72 mM/L) compared to the D-lactic acid produced by strains from healthy vagina with vaginal pH ∼ 4 (8.04 ± 1.07 mM/L) culture supernatant of 0.5 McFarland concentration (P < 0.001).

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Acknowledgements

We express our sincere appreciation to all of the women who participated in the study.

This study was supported by a Research Grant of the Department of Biotechnology (DBT), Govt. of India. K.B.G. is a recipient of the University Grants Commission (UGC) Fellowship.

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Correspondence to G. P. Talwar.

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Garg, K.B., Ganguli, I., Kriplani, A. et al. Metabolic properties of lactobacilli in women experiencing recurring episodes of bacterial vaginosis with vaginal pH ≥ 5. Eur J Clin Microbiol Infect Dis 29, 123 (2010). https://doi.org/10.1007/s10096-009-0818-1

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Keywords

  • Lactobacillus
  • Bacterial Vaginosis
  • Probiotic Lactobacillus
  • Bromocresol Purple
  • Nugent Score