Abstract
The Platelia Aspergillus assay tested positive in 8 of 11 patients with disseminated histoplasmosis. While other available methods for diagnosis have several drawbacks, this cross-reactivity is particularly valuable in the perspective of practitioners outside the USA who cannot use the test detecting antigen of Histoplasma capsulatum.
References
Genot S, Franck J, Forel J-M, Rebaudet S, Ajzenberg D, Maues de Paula A, Dardé M-L, Stein A, Ranque S (2007) Severe Toxoplasma gondii I/III recombinant genotype encephalitis in a HIV patient. J Clin Microbiol (in press)
Girouard G, Lachance C, Pelletier R (2007) Observations on (1-3)-{beta}-D-glucan detection as a diagnostic tool in endemic mycosis caused by Histoplasma or Blastomyces. J Med Microbiol 56(Pt 7):1001–1002
Dalle F, Charles PE, Blanc K, Caillot D, Chavanet P, Dromer F, Bonnin A (2005) Cryptococcus neoformans Galactoxylomannan contains an epitope(s) that is cross-reactive with Aspergillus Galactomannan. J Clin Microbiol 43(6):2929–2931
Wheat LJ, Hackett E, Durkin M, Connolly P, Petraitiene R, Walsh TJ, Knox K, Hage C (2007) Histoplasmosis-associated cross-reactivity in the BioRad Platelia Aspergillus enzyme immunoassay. Clin Vaccine Immunol 14(5):638–640
Wheat LJ (2006) Histoplasmosis: a review for clinicians from non-endemic areas. Mycoses 49(4):274–282
Wheat LJ (2006) Antigen detection, serology, and molecular diagnosis of invasive mycoses in the immunocompromised host. Transpl Infect Dis 8(3):128–139
Acknowledgments
This work has been presented in part at the 16th Congress of the International Society for Human and Animal Mycology, 25–29 June 2006, Paris, France: Abstract P-0293 and P-0299.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Ranque, S., Pelletier, R., Michel-Nguyen, A. et al. Platelia Aspergillus assay for diagnosis of disseminated histoplasmosis. Eur J Clin Microbiol Infect Dis 26, 941–943 (2007). https://doi.org/10.1007/s10096-007-0380-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10096-007-0380-7