Changes in antimicrobial resistance of Escherichia coli causing urinary tract infections in hospitalized children

  • M. Fritzsche
  • R.A. Ammann
  • S. Droz
  • M.G. Bianchetti
  • C. Aebi
Brief Report

Urinary tract infections (UTI) are among the most common bacterial infections of childhood. Rapid recognition and appropriate antimicrobial therapy relieve symptoms and prevent renal damage [1]. Since therapy for suspected UTI is usually initiated before the responsible organism and its susceptibility to antimicrobial agents are known, the rational choice of an antibiotic relies on local epidemiologic data. In infants and young children without a known urinary tract malformation, Escherichia coli is responsible for the vast majority of episodes [2, 3]. Recent studies suggest that in these patients intravenous antibiotic therapy for acute pyelonephritis may no longer be warranted, and that most patients can be treated safely with oral third-generation cephalosporins [3, 4]. However, since outpatient oral therapy for acute pyelonephritis requires certainty that the drug used is active against the expected pathogens, this trend is somewhat at odds with the increasing antimicrobial...


Urinary Tract Infection Acute Pyelonephritis Febrile Urinary Tract Infection Transurethral Catheterization Urinary Tract Malformation 
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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • M. Fritzsche
    • 1
  • R.A. Ammann
    • 1
  • S. Droz
    • 2
  • M.G. Bianchetti
    • 3
  • C. Aebi
    • 1
  1. 1.Department of Pediatrics and Institute for Infectious DiseasesUniversity of BernBernSwitzerland
  2. 2.Institute for Infectious DiseasesUniversity of BernBernSwitzerland
  3. 3.Ospedale San GiovanniBellinzonaSwitzerland

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