Abstract
The purpose of this study was to clarify whether bacteria are transferred from the portal venous system into central venous blood during the placement of a transjugular portosystemic stent shunt (TIPSS). TIPSS was created in 30 consecutive cirrhotic patients for recurrent variceal bleeding (n=12), refractory ascites (n=16), or hepatorenal syndrome (n=2). Microbiological analysis was performed prospectively on central venous blood before and on portal venous blood immediately after puncture of the portal vein. Twenty minutes after the placement of TIPSS, another sample of central venous blood was obtained. None of the first two sets of blood cultures showed bacterial growth, so that no bacterial transfer was seen at the time of TIPSS placement. Four of the third sets of blood samples showed skin and mouth flora, interpreted as iatrogenic contamination.
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Cohnen, M., Lüthen, R., Däubener, W. et al. Lack of Portosystemic Bacterial Translocation in Patients with Liver Cirrhosis after Placement of Transjugular Shunt. Eur J Clin Microbiol Infect Dis 22, 310–312 (2003). https://doi.org/10.1007/s10096-003-0911-9
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DOI: https://doi.org/10.1007/s10096-003-0911-9