Abstract.
The genodiversity of Staphylococcus aureus isolates from the Nottingham region of the United Kingdom was compared with isolates from the Freiburg region of Germany. The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) isolates was higher in Nottingham than in Freiburg. In patients from Nottingham hospitals, 80% of MRSA isolates were classical epidemic MRSA-15, but genotypic variants of epidemic MRSA-15 comprised 72% of isolates from Nottingham community-based patients. In contrast, MRSA isolates from Freiburg showed greater diversity, but 47% and 23% of isolates, respectively, belonged to two predominant MRSA genotypes found in isolates from both hospitalised and community-based patients. The results suggest that genodiversity becomes increasingly more confined in settings with a higher frequency and longer duration of MRSA prevalence.
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Jonas, .D., Towner, .K., Loerwald, .M. et al. Diversity of Staphylococcus aureus Strains Isolated from Two European Regions with Different Prevalences of Methicillin Resistance. Eur J Clin Microbiol Infect Dis 21, 880–883 (2002). https://doi.org/10.1007/s10096-002-0842-x
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DOI: https://doi.org/10.1007/s10096-002-0842-x