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Two Cases of Fungemia due to Candida lusitaniae and a Literature Review

European Journal of Clinical Microbiology and Infectious Diseases volume 21, pages 294–299 (2002)Cite this article

Abstract.

Reported here are two cases of candidemia caused by Candida lusitaniae that occurred in two immunocompromised patients at Hospital Universitario "La Fe" in Valencia, Spain. Case 1 involved a low-birth-weight premature infant with congenital nephrotic syndrome who was successfully treated with amphotericin B, and case 2 involved a 50-year old woman with a high-grade malignancy lymphoma who succumbed to the infection. Antifungal susceptibility testing of the Candida lusitaniae isolates recovered from both patients revealed sensitivity to amphotericin, 5-flucytosine and fluconazole. Results are presented and discussed together with a comprehensive review of the literature, covering all previously reported cases of fungemia caused by this emerging pathogen.

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Affiliations

  1. Servicio de Microbiología, Hospital Universitario La Fe, Valencia, Spain

    A. Viudes, J. Pemán, P. Ubeda & M. Gobernado

  2. Unidad de Bacteriología Experimental, Hospital Universitario La Fe, Valencia, Spain

    E. Cantón

  3. Unidad de Enfermedades Infecciosas, Hospital Universitario La Fe, Valencia, Spain

    M. Salavert

  4. Departament of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, South Texas, Centers for Biology in Medicine, Texas Research Park, 15355 Lambda Drive, San Antonio, TX 78245, USA

    J. López-Ribot

Authors
  1. A. Viudes
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  2. J. Pemán
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  3. E. Cantón
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  4. M. Salavert
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  5. P. Ubeda
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  6. J. López-Ribot
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  7. M. Gobernado
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Viudes, A., Pemán, J., Cantón, E. et al. Two Cases of Fungemia due to Candida lusitaniae and a Literature Review. Eur J Clin Microbiol Infect Dis 21, 294–299 (2002). https://doi.org/10.1007/s10096-002-0713-5

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  • DOI: https://doi.org/10.1007/s10096-002-0713-5

Keywords

  • Fluconazole
  • Clinical Microbiology
  • Flucytosine
  • Clinical Infectious Disease
  • Congenital Nephrotic Syndrome