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High-frequency electrical stimulation of the subthalamic nucleus in Parkinson's disease: kinetic and kinematic gait analysis

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Abstract.

In the advanced phase of Parkinson's disease (PD), gait disturbances represent one of the main causes of disability. Several studies demonstrated that high-frequency electrical stimulation (HFS) of the subthalamic nucleus (STN) significantly improves the motor symptoms of PD. This study was finalised to quantitatively analyze the effect of STN HFS on gait of PD patients, through a three-dimensional gait analysis system. Ten PD patients were studied, with and without STN HFS. The results demonstrated that STN HFS significantly improves all the main gait parameters in PD patients.

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Authors and Affiliations

  1. U.O.A. of Neurology, ASL 19, Asti, Italy, , , , , , IT

    M. Rizzone

  2. Department of Neurosciences, University of Turin, Turin, Italy, , , , , , IT

    M. Ferrarin, A. Pedotti & M. Recalcati

  3. U.O.A. of Neurosurgery, Azienda Ospedaliera CTO-CRF M. Adelaide, Turin, Italy, , , , , , IT

    B. Bergamasco, E. Bosticco, P. Perozzo, A. Tavella, E. Torre & L. Lopiano

  4. Bioengineering Centre, Don Carlo Gnocchi Foundation, Politecnico of Milan, Milan, Italy, , , , , , IT

    M. Lanotte & A. Melcarne

Authors
  1. M. Rizzone
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  2. M. Ferrarin
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  3. A. Pedotti
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  4. B. Bergamasco
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  5. E. Bosticco
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  6. M. Lanotte
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  7. P. Perozzo
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  8. A. Tavella
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  9. E. Torre
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  10. M. Recalcati
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  11. A. Melcarne
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  12. L. Lopiano
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Correspondence to M. Rizzone

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Rizzone, M., Ferrarin, M., Pedotti, A. et al. High-frequency electrical stimulation of the subthalamic nucleus in Parkinson's disease: kinetic and kinematic gait analysis. Neurol Sci 23 (Suppl 2), s103–s104 (2002). https://doi.org/10.1007/s100720200090

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  • DOI: https://doi.org/10.1007/s100720200090

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