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Prevalence of hallucinations in Parkinson’s patients: meta-analysis of International studies

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Abstract

Background

Parkinson’s disease (PD) is one of the common causes of disability in the elderly. This study aims to estimate the prevalence of hallucinations in Parkinson’s patients in the world.

Methods

A systematic review of PubMed/Medline, ISI Web of Knowledge, and Google Scholar was conducted from 2017 to 2022. This study investigated the prevalence of hallucinations in Parkinson’s patients. Point prevalence was analyzed with a 95% confidence interval. The variances of each study were calculated using the binomial distribution formula The researcher used Cochrane Q-test with a significance level of less than 0.1 to check the heterogeneity between studies and the change index assigned to heterogeneity I2. Due to the heterogeneity between the studies, the random effects model was used to combine the results of the studies. All statistical analyses were performed by STATA version 14 software using meta-analysis commands.

Results

Reports indicated that the prevalence of hallucinations in Parkinson’s patients in 32 studies was 28% (0.22–0.34 = 95%CI). The highest prevalence was 34% and 95% CI = 0.07– 0.61 in developing countries and 27% with CI = 0.33–0.21 in developed countries. Reports showed the prevalence in men was 30% (CI = 0.22–0.38) and in women 23% (95% CI = 0.14–0.31).

Conclusions

Considering the relatively high prevalence of hallucinations in these patients, checking up for the presence of hallucinations on every visit of Parkinson’s patients is recommended, and providing appropriate treatment for that is necessary.

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Authors and Affiliations

  1. Library and Information Sciences, Department of General Courses, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran

    Somayye Nadi Ravandi

  2. Department of Neurology, School of Medicine, Shahid Beheshti Hospital, Kashan University of Medical Sciences, Kashan, Iran

    Ebrahim Kouchaki

  3. Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, Iran

    Fatemeh Sadat Asgarian

Authors
  1. Somayye Nadi Ravandi
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  2. Ebrahim Kouchaki
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  3. Fatemeh Sadat Asgarian
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Corresponding author

Correspondence to Fatemeh Sadat Asgarian.

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Ethical approval

The study was approved by the Ethics Committee of Kashan University of Medical Sciences, Kashan, Iran, and conducted under number (IR.KAUMS.NUHEPM.REC.1402.001).

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Ravandi, S.N., Kouchaki, E. & Asgarian, F.S. Prevalence of hallucinations in Parkinson’s patients: meta-analysis of International studies. Neurol Sci 44, 3389–3394 (2023). https://doi.org/10.1007/s10072-023-06831-8

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  • DOI: https://doi.org/10.1007/s10072-023-06831-8

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