Skip to main content

Advertisement

Log in

Perfusion imaging averting intravenous thrombolysis in stroke mimics

  • Letter to the Editor
  • Published:
Neurological Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Tsivgoulis G, Katsanos AH, Schellinger PD, Köhrmann M, Caso V, Palaiodimou L, Magoufis G, Arthur A, Fischer U, Alexandrov AV (2018) Advanced neuroimaging in stroke patient selection for mechanical thrombectomy. Stroke 49(12):3067–3070

    Article  Google Scholar 

  2. Campbell BCV, Ma H, Ringleb PA, Parsons MW, Churilov L, Bendszus M, Levi CR, Hsu C, Kleinig TJ, Fatar M, Leys D, Molina C, Wijeratne T, Curtze S, Dewey HM, Barber PA, Butcher KS, de Silva DA, Bladin CF, Yassi N, Pfaff JAR, Sharma G, Bivard A, Desmond PM, Schwab S, Schellinger PD, Yan B, Mitchell PJ, Serena J, Toni D, Thijs V, Hacke W, Davis SM, Donnan GA, Donnan GA, Davis SM, Ma H, Campbell BCV, Churilov L, Parsons MW, Yan B, Mitchell PJ, Yassi N, Sharma G, Desmond PM, Oxley T, Wu TY, Shah D, Zhao H, Rodrigues E, Salvaris P, Alemseged F, Ng F, Williams C, Ng JL, Tu HTH, McDonald A, Jackson D, Tsoleridis J, McCoy R, Pesavento L, Weir L, Bivard A, Kleinig TJ, Patel S, Harvey J, Mahadevan J, Cheong E, Balabanski A, Waters M, Drew R, Cranefield J, Wijeratne T, Mackey E, Celestino S, Low E, Dewey HM, Bladin CF, Loh PS, Choi PM, Coote S, Frost T, Hogan K, Ding C, McModie S, Zhang WW, Kyndt C, Moore A, Ross Z, Liu J, Miteff F, Levi CR, Ang T, Spratt N, Garcia-Esperon C, Kaauwai L, Phan TG, Ly J, Singhal S, Clissold B, Wong K, Krause M, Day S, Sturm J, O'Brian B, Grimley R, Thijs V, Simpson M, Lee-Archer M, Brodtmann A, Coulton B, Young D, Wong AA, Muller C, Field DK, Vallat W, Maxwell V, Bailey P, Sabet A, Mishra S, Tan M, George K, Barber PA, Zhao L, Meretoja A, Curtze S, Tatlisumak T, Sibolt G, Tiainen M, Koivu M, Aarnio K, Virta J, Kasari O, Eirola S, Sun MC, Chen TC, Chuang CS, Chen YY, Lin CM, Ho SC, Hsiao PM, Tsai CH, Huang WS, Yang YW, Huang HY, Wang WC, Liu CH, Lu MK, Lu CH, Kung WL, Jiang SK, Wu YH, Huang SC, Tseng CH, Tseng LT, Guo YC, Lin D, Hsu CT, Kuan CW, Hsu JP, Tsai HT, Suzuki M, Sun Y, Chen HF, Lu CJ, Lin CH, Huang CC, Chu HJ, Lee CY, Chang WH, Lo YC, Hsu YT, Chen CH, Sung PS, Ysai CL, Jeng JS, Tang SC, Tsai LK, Yeh SJ, Lee YC, Wang YT, Chung TC, Hu CJ, Chan L, Chiou YW, Lien LM, Yeh HL, Yeh JH, Chen WH, Lau CL, Chang A, Lee IY, Huang MY, Lee JT, Peng GS, Lim JC, Hsu YD, Lin CC, Cheng CA, Yen CH, Yang FC, Hsu CH, Sung YF, Tsai CK, Tsai CL, Hsiao PM, Lee A, Hankey G, Blacker D, Gerraty R, Chen CI, Hsu CS, Cowley E, McCoy R, Sallaberger M, Snow B, Kolbe J, Stark R, King J, Macdonnell R, Attia J, D'Este C, Bernhardt J, Carey L, Cadilhac D, Anderson C, Howells D, Barber A, Connelly A, Macleod M, O'Collins V, Wilson W, Macaulay L, Bendszus M, Bluhmki E, Eschenfelder C, Hacke W, Molina C, Leys D, Ringleb P, Schellinger P, Schwab S, Toni D, Wahlgren N, Wardlaw J, Oppenheim C, Lees KR, Kaste M, von Kummer R, Chatellier G, Laage R, Nuñez X, Ehrenkrona C, Svenson AS, Cove L, Niederkorn K, Gruber F, Kapeller P, Mikulik R, Mas JL, Berrouschot J, Sobesky J, Köhrmann M, Steiner T, Kessler C, Fatar M, Dziewas R, Poli S, Althaus-Knaurer K, Bovi P, Rodriguez AL, Arenillas JF, Muir K, Veltkamp R, Dixit A, Muddegowda G, Kala L, de Silva DA, Butcher KS, Byrnes G, Peeters A, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Tress BM, McNeil J, Burns R, Johnston C, Williams M (2019) Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data. Lancet 394(10193):139–147

    Article  Google Scholar 

  3. Psychogios K, Magoufis G, Safouris A, Kargiotis O, Katsanos AH, Spiliopoulos S, Papageorgiou E, Palaiodimou L, Brountzos E, Stamboulis E, Tsivgoulis G (2020) Eligibility for intravenous thrombolysis in acute ischemic stroke patients presenting in the 4.5-9 h window. Neuroradiology 62(6):733–739

    Article  Google Scholar 

  4. Kappler J, Mohr S, Steinmetz H (1997 Sep) Cerebral vasomotor changes in the transient syndrome of headache with neurologic deficits and CSF lymphocytosis (HaNDL). Headache. 37(8):516–518

    Article  CAS  Google Scholar 

  5. Zinkstok SM, Engelter ST, Gensicke H, Lyrer PA, Ringleb PA, Artto V, Putaala J, Haapaniemi E, Tatlisumak T, Chen Y, Leys D, Sarikaya H, Michel P, Odier C, Berrouschot J, Arnold M, Heldner MR, Zini A, Fioravanti V, Padjen V, Beslac-Bumbasirevic L, Pezzini A, Roos YB, Nederkoorn PJ (2013) Safety of thrombolysis in stroke mimics: results from a multicenter cohort study. Stroke 44:1080–1084

    Article  Google Scholar 

  6. Tsivgoulis G, Zand R, Katsanos AH, Goyal N, Utchino K, Chang J et al (2015) Safety of intravenous thrombolysis in stroke mimics: prospective 5-year study and comprehensive meta-analysis. Stroke 46:1281–1287

    Article  CAS  Google Scholar 

  7. Keselman B, Cooray C, Vanhooren G, Bassi P, Consoli D, Nichelli P, Peeters A, Sanak D, Zini A, Wahlgren N, Ahmed N, Mazya MV (2019) Intravenous thrombolysis in stroke mimics: results from the SITS International Stroke Thrombolysis Register. Eur J Neurol 26(8):1091–1097

    Article  CAS  Google Scholar 

  8. Polymeris AA, Curtze S, Erdur H, Hametner C, Heldner MR, Groot AE, TRISP Collaborators et al (2019) Intravenous thrombolysis for suspected ischemic stroke with seizure at onset. Ann Neurol 86(5):770–779

    Article  CAS  Google Scholar 

  9. Campbell BC, Weir L, Desmond PM, Tu HTH, Hand PJ, Yan B et al (2013) CT perfusion improves diagnostic accuracy and confidence in acute ischaemic stroke. J Neurol Neurosurg Psychiatry 84(6):613–618

    Article  Google Scholar 

  10. Dehkharghani S, Bammer R, Straka M, Albin LS, Kass-Hout O, Allen JW, Rangaraju S, Qiu D, Winningham MJ, Nahab F (2015) Performance and predictive value of a user-independent platform for CT perfusion analysis: threshold-derived automated systems outperform examiner-driven approaches in outcome prediction of acute ischemic stroke. Am J Neuroradiol 36:1419–1425

    Article  CAS  Google Scholar 

  11. Siegler JE, Rosenberg J, Cristancho D, Olsen A, Pulst-Korenberg J, Raab L, Cucchiara B, Messé SR (2020) Computed tomography perfusion in stroke mimics. Int J Stroke 15(3):299–307

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Klearchos Psychogios.

Ethics declarations

Ethical approval

None.

Conflict of interest

The authors declare no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

ESM 1

Supplemental figure CT-perfusion of a 39-year old man presenting with acute aphasia and right hemiparesis. (a-d) Prolonged Time To Peak (TTP) over 4 sec, in more than one arterial territories (white arrows). (e) Automated Tmax maps (postprocessed by RAPID software) demonstrated a 10ml region of Tmax >4 sec prolongation (shown in blue). (f) Subsequent DWI MRI confirms the absence of acute ischemia. (PNG 2559 kb)

High resolution image (TIFF 34914 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Psychogios, K., Kargiotis, O., Safouris, A. et al. Perfusion imaging averting intravenous thrombolysis in stroke mimics. Neurol Sci 42, 2591–2594 (2021). https://doi.org/10.1007/s10072-021-05090-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10072-021-05090-9

Navigation