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First case report of fungal meningitis due to a polypore mushroom Irpex lacteus

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Abstract

A 73-year-old Japanese man with a medical history of sarcoidosis was diagnosed with meningitis caused by an undetermined fungus. For further identification, the cerebrospinal fluid sample was analyzed for the rDNA internally transcribed spacer regions, and the fungus was identified as Irpex lacteus. I. lacteus is classified under phylum Basidiomycota and is a wood-rotting bracket mushroom. Although there is no standard treatment regimen for I. lacteus infections, amphotericin B was effective in this patient. Herein, we present, to our knowledge, the first reported case of fungal meningitis caused by I. lacteus, its treatment course, and review relevant published literature.

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Fig. 1

Data availability

The data that support the findings of this study are available from the corresponding author, Y.K., upon reasonable request.

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Authors and Affiliations

  1. Department of Neurology, Tosei General Hospital, 160 Nishioiwake-cho, Seto, Aichi, 489-8642, Japan

    Yuya Kano & Hiroyuki Yuasa

  2. Department of Neurology, Nagoya City East Medical Center, Wakamizu 1-2-23, Chikusa ward, Nagoya, Aichi, 464-8547, Japan

    Yuya Kano & Kentaro Yamada

  3. Department of Clinical Infectious Diseases, Aichi Medical University, Nagakute, Aichi, Japan

    Yuka Yamagishi

  4. Department of Infectious Diseases, Medical Mycology Research Center, Chiba University, Chiba, Japan

    Katsuhiko Kamei

  5. Department of Infectious Diseases, Tosei General Hospital, Seto, Aichi, Japan

    Yoshikazu Mutoh

  6. Department of Neurology, Graduate School of Medicine, Nagoya City University, Nagoya, Aichi, Japan

    Noriyuki Matsukawa

Authors
  1. Yuya Kano
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  2. Yuka Yamagishi
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  3. Katsuhiko Kamei
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  4. Yoshikazu Mutoh
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  5. Hiroyuki Yuasa
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  6. Kentaro Yamada
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  7. Noriyuki Matsukawa
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Corresponding author

Correspondence to Yuya Kano.

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The authors declare that they have no conflict of interest.

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The Ethics Committee of Tosei General Hospital approved this case report, and informed consent was obtained from the patient to use the data for academic purposes.

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Informed consent was obtained from the patient described in this study.

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Kano, Y., Yamagishi, Y., Kamei, K. et al. First case report of fungal meningitis due to a polypore mushroom Irpex lacteus. Neurol Sci 42, 2075–2078 (2021). https://doi.org/10.1007/s10072-020-04947-9

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  • DOI: https://doi.org/10.1007/s10072-020-04947-9

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