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Seronegative limbic encephalitis

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We thank Alexandra L. Salewski, MSc, for the English revision of the manuscript.

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Correspondence to Carlos de Cabo.

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All examinations and interventions were performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki (amended version from 2013) and complemented by the Declaration of Taipei on Ethical Considerations regarding Health Databases and Biobanks in 2016.

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Suppl. Fig. 1

LTS. Left temporal seizure. Legend: Longitudinal bipolar montage, sensitivity 10uV/mm, timebase 15mm/s, LFF 1 Hz, HFF 15 Hz. Seizure starts with a spike-and-wave in left temporal electrodes, T3>T5-F7 (red arrow) followed by a low-amplitude spiky activity that evolves into a lobar spike-and-wave pattern on delta range in left temporal. Seizure subsequently propagates to the right temporal lobe with an (asymmetric, left more than right) bitemporal high amplitude polyspikes on alfa range, that progressively increases in amplitude and decreases in frequency, finalizing abruptly (red discontinuous line). The patient did not refer symptoms, but piloerection in left arm and facial flushing was observed in the physical exploration during seizure. (JPG 1162 kb)

Suppl. Fig. 2.

RTS. Subclinical right temporal seizure: Legend: Longitudinal bipolar montage, sensitivity 10uV/mm, timebase 15mm/s, LFF 0.5 Hz, HFF 15 Hz. Seizure starts in right anterior-temporal electrodes F8>T4 (red arrow) with a spiky incremental theta activity that progressively increases in amplitude. The seizure remains limited to anterior-temporal electrodes without propagation to adjacent regions. The patient had no symptoms and physical exploration was normal during the seizure. (JPG 470 kb)

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Sánchez-Larsen, Á., de Cabo, C. Seronegative limbic encephalitis. Neurol Sci 41, 205–208 (2020).

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