Neurological Sciences

, Volume 40, Issue 3, pp 645–647 | Cite as

A fatal back pain: report of two cases of diffuse large B cell/Burkitt-like nervous system lymphoma

  • Ivana MarkovicEmail author
  • Jelena Saric Sucic
  • Stjepan Juric
  • Marina Titlic
  • Silvio Basic
Letter to the Editor

Dear Editor-in-Chief,

Primary central nervous system lymphoma (PCNSL) is an uncommon variant of the extranodal non-Hodgkin lymphoma which involves different structures of the nervous system. It accounts for 2.7% of all nervous system malignancies [1]. Most PCNSL are diffuse large B cell lymphomas (DLBCLs). Diffuse large B cell lymphoma/Burkitt-like (DLBCL/BL) is a term assigned to an aggressive B cell lymphoma with features intermediate between the diffuse large B cell lymphoma and the Burkitt-like lymphoma in the updated WHO classification of tumors of the hematopoietic and lymphoid tissues [2]. There are no data on the incidence and prognosis of the nervous system DLBCL/BL since there has been only one report of DLBCL/BL with cerebral and involvement of the cauda equina which suggested DLBCL/BL could be PCNSL with a very aggressive nature [3]. We present a case of PCNSL and a case of primary lymphoma of peripheral nerve (PLPN), both DBCL/BL, with an initial presentation as lower...


Compliance with ethical standards

Informed consent

Informed consent was obtained from both patients included in this paper.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Faculty of Dental Medicine and HealthJosip Juraj Strossmayer University of OsijekOsijekCroatia
  2. 2.Department of NeurologyUniversity Hospital DubravaZagrebCroatia
  3. 3.Clinical Department of NeurologyOsijek University Hospital CenterOsijekCroatia
  4. 4.Clinical Department of NeurologySplit University Hospital CenterSplitCroatia

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