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Authors and Affiliations
Contributions
Mohammad Rohani: executed the study and drafted the manuscript
Alfonso Fasano: revised the manuscript for intellectual content
Anthony E Lang: revised the manuscript for intellectual content
Babk Zamani: revised the manuscript for intellectual content
Leila Javanparast: did genetic testing
Mohammad Masoud Rahimi Bidgoli:did genetic testing
Afagh Alavi: did genetic testing and revised the manuscript for intellectual content
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Electronic supplementary materials
Supplementary Figure 1
Results of DUET prediction. The results show the folding free energy changes upon mutation. Minus values of the Gibbs free energy (ΔΔG) predict as destabilizing. Arrow shows position of Leu278. (PNG 1610 kb)
Supplementary Figure 2
Sequencing chromatogram of PANK2 mutation observed in the Iranian patient. Results of direct sequencing of PANK2 gene using forward (top) and reverse (down) primers. (PNG 2039 kb)
Supplementary table 1
(DOCX 13 kb)
Video 1
Multiple motor tics are evident especially when he is distracted by asking to do finger tapping. (MPG 14644 kb)
Video 2
On walking there is mild dystonic posture of feet and great toes more on the right side. (MPG 4312 kb)
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Rohani, M., Fasano, A., Lang, A.E. et al. Pantothenate kinase-associated neurodegeneration mimicking Tourette syndrome: a case report and review of the literature. Neurol Sci 39, 1797–1800 (2018). https://doi.org/10.1007/s10072-018-3472-5
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DOI: https://doi.org/10.1007/s10072-018-3472-5