Mindfulness meditation for chronic migraine in pediatric population: a pilot study
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Chronic migraine (CM) is a highly disabling condition characterized by at least 15 days with headache per month and is often associated with overuse of symptomatic drugs and it impairs patients’ emotional, social, and work/school functioning. Among adults, CM prevalence is around 1–4%, and among adolescents, it is around 2%. CM is characterized by changes in the structures involved in pain-related circuits with increased sensitivity to painful (hyperalgesia) and to non-painful stimuli (allodynia). Specific biomarkers in pediatric patients with migraine have been evaluated. The study showed a reduction in IL-1β, IL-6, TNF-α levels, and in clinical indexes related to headache: frequency, intensity, duration, and disability in patients treated with pharmacological prophylaxis . However, no studies that have shown any effect on biological markers induced by non-pharmacological approaches. There are many pharmacological prophylactic therapies, but these are effective in 30–50% of cases:...
Compliance with ethical standards
All procedures were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments. Informed consent was obtained from all individual participants included in the study.
Conflict of interest
The authors declare that they have no conflict of interest.
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