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Expanding the spectrum of movement disorders in Klinefelter syndrome

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Author information

Authors and Affiliations

  1. Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal

    Margherita Fabbri

  2. Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Via Cherasco 15, 10124, Turin, Italy

    Maurizio Zibetti, Tiziana Martone & Leonardo Lopiano

Authors
  1. Margherita Fabbri
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  2. Maurizio Zibetti
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  3. Tiziana Martone
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  4. Leonardo Lopiano
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Corresponding author

Correspondence to Maurizio Zibetti.

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Conflict of interest

Dr. Margherita Fabbri: no conflict of interest to report. Stock ownership in medically related fields: none; Consultancies: none; Advisory Boards: none; Partnership: none; Honoraria to speak: none; Grants: none; Intellectual property rights: none; Expert testimony: none; Employment: PhD student, Instituto de Medicina Molecular, Lisbon; Contracts: none; Royalties: none; Other: none.

Dr. Maurizio Zibetti: no conflict of interest to report. Honoraria to speak and grants: Medtronic, Zambon, UCB Pharma, and AbbVie.

Tiziana Martone no conflict of interest to report. Stock ownership in medically related fields: none; Consultancies: none; Advisory boards: none; Partnership: none; Honoraria to speak: none; Grants: none; Intellectual property rights: none; Expert testimony: none; Contracts: none; Royalties: none; Other: none.

Professor Leonardo Lopiano: no conflict of interest to report. Honoraria to speak and grants: Medtronic, UCB Pharma, and AbbVie.

Electronic supplementary material

Video 1

In MED ON (levodopa equivalent daily dose: 1500 mg), patient shows upper limb asymmetric rest tremor (right side predominance), postural and intentional tremor, worsening during writing, mild bradykinesia (slight left side predominance), an anterocollis and a mild Pisa syndrome (with left shoulder elevation)”. Pull test was normal (not showed). (MP4 101391 kb)

Fig. 1

18Ffluorodopa positron emission tomography: asymmetric decrease of the uptake in the putamen (right > left) (GIF 548 kb)

High Resolution Image (TIFF 685 kb)

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Fabbri, M., Zibetti, M., Martone, T. et al. Expanding the spectrum of movement disorders in Klinefelter syndrome. Neurol Sci 39, 1303–1304 (2018). https://doi.org/10.1007/s10072-018-3296-3

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  • DOI: https://doi.org/10.1007/s10072-018-3296-3

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