Neurological Sciences

, Volume 39, Issue 4, pp 641–645 | Cite as

Techniques of cognitive rehabilitation in patients with disorders of consciousness: a systematic review

  • Elena La Gattuta
  • Francesco Corallo
  • Viviana Lo Buono
  • Simona De Salvo
  • Fabrizia Caminiti
  • Carmela Rifici
  • Antonella Alagna
  • Francesca Arcadi
  • Alessia Bramanti
  • Silvia Marino
Review Article


Acquired brain injury can produce severe impairments of alertness, cognition, behavior, and, sometimes, an impairment of consciousness. Several studies defined the criteria to distinguish the different level of disorders of consciousness (DOC) and many tools to evaluate awareness, alertness, and response to stimuli were created. The aim of this review is to assess the advanced research of rehabilitative protocols and which rehabilitative techniques are used in the care of DOC patients.


Disorder of consciousness Rehabilitation Coma state Minimally conscious state Vegetative state 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants and/or animals

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was not necessary because the present study consist of a literature revision.


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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  • Elena La Gattuta
    • 1
  • Francesco Corallo
    • 1
  • Viviana Lo Buono
    • 1
  • Simona De Salvo
    • 1
  • Fabrizia Caminiti
    • 1
  • Carmela Rifici
    • 1
  • Antonella Alagna
    • 1
  • Francesca Arcadi
    • 1
  • Alessia Bramanti
    • 1
  • Silvia Marino
    • 1
    • 2
  1. 1.IRCCS Centro Neurolesi Bonino PulejoMessinaItaly
  2. 2.Department of Biomedical and Dental Sciences and Morphological and Functional ImagingUniversity of MessinaMessinaItaly

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