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Accompanying migrainous features in pediatric migraine patients with restless legs syndrome

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Abstract

The present study aimed to examine the frequency of restless legs syndrome (RLS) in pediatric patients with migraine and tension-type headache (TTH) and to investigate accompanying migrainous symptoms, sleep characteristics, as well as levels of serum ferritin between the pediatric migraine patients with RLS and those without RLS. We included 65 consecutive patients diagnosed with migraine, 20 patients with TTH, and 97 headache-free children in our study. Demographic, clinical, and laboratory data were noted. The presence of a primary headache was diagnosed using the ICHD-II criteria, and RLS was determined with face-to-face interviews conducted by an experienced neurologist based on the revised International RLS Study Group criteria for pediatrics. The frequency of RLS in pediatric migraine and TTH patients was significantly higher than in the controls (p = 0.0001 and p = 0.025, respectively). The frequencies of allodynia, vertigo/dizziness, and self-reported frequent arousals were significantly higher, and serum ferritin levels were significantly lower in migraine patients with RLS compared to those without RLS (p = 0.05, p = 0.028, p = 0.02, and p = 0.038, respectively). Our study suggests that the frequency of RLS is higher in pediatric migraine and TTH patients compared to controls. Therefore, pediatric headache patients should be questioned about the presence of RLS, as this co-occurrence may lead to more frequent accompanying migrainous symptoms and sleep disturbances.

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Authors and Affiliations

  1. Department of Neurology, Cerrahpasa School of Medicine, Istanbul University, 34098, Istanbul, Turkey

    Melis Sohtaoğlu Sevindik, Baki Göksan, Feray Karaali Savrun, Harika Ozhan & Derya Uludüz

  2. Department of Neurology, School of Medicine, Suleyman Demirel University, Isparta, Turkey

    Seden Demirci

  3. Department of Neurology, Mersin University Medical School, Mersin, Turkey

    Aynur Özge

  4. Department of Pediatrics, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey

    Hatice Onur

  5. Department of Child and Adolescent Psychiatry, Mersin University Medical School, Mersin, Turkey

    Veli Yıldırım

  6. Cerrahpasa School of Medicine, Istanbul University, Istanbul, Turkey

    Ismail Simsek

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  1. Melis Sohtaoğlu Sevindik
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  2. Seden Demirci
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  3. Baki Göksan
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Correspondence to Derya Uludüz.

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Sevindik, M.S., Demirci, S., Göksan, B. et al. Accompanying migrainous features in pediatric migraine patients with restless legs syndrome. Neurol Sci 38, 1677–1681 (2017). https://doi.org/10.1007/s10072-017-3045-z

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  • DOI: https://doi.org/10.1007/s10072-017-3045-z

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