The effect of Wi-Fi electromagnetic waves in unimodal and multimodal object recognition tasks in male rats
Wireless internet (Wi-Fi) electromagnetic waves (2.45 GHz) have widespread usage almost everywhere, especially in our homes. Considering the recent reports about some hazardous effects of Wi-Fi signals on the nervous system, this study aimed to investigate the effect of 2.4 GHz Wi-Fi radiation on multisensory integration in rats. This experimental study was done on 80 male Wistar rats that were allocated into exposure and sham groups. Wi-Fi exposure to 2.4 GHz microwaves [in Service Set Identifier mode (23.6 dBm and 3% for power and duty cycle, respectively)] was done for 30 days (12 h/day). Cross-modal visual-tactile object recognition (CMOR) task was performed by four variations of spontaneous object recognition (SOR) test including standard SOR, tactile SOR, visual SOR, and CMOR tests. A discrimination ratio was calculated to assess the preference of animal to the novel object. The expression levels of M1 and GAT1 mRNA in the hippocampus were assessed by quantitative real-time RT-PCR. Results demonstrated that rats in Wi-Fi exposure groups could not discriminate significantly between the novel and familiar objects in any of the standard SOR, tactile SOR, visual SOR, and CMOR tests. The expression of M1 receptors increased following Wi-Fi exposure. In conclusion, results of this study showed that chronic exposure to Wi-Fi electromagnetic waves might impair both unimodal and cross-modal encoding of information.
KeywordsWi-Fi Novel object recognition Memory Muscarinic receptor GABA
This work was supported by a grant from the Research Deputy of Rafsanjan University of Medical Sciences.
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Conflict of interest
The authors declare that there are no conflicts of interest.
- 5.Naziroglu M, Celik O, Ozgul C, Cig B, Dogan S, Bal R, Gumral N, Rodriguez AB, Pariente JA (2012) Melatonin modulates wireless (2.45 GHz)-induced oxidative injury through TRPM2 and voltage gated Ca(2+) channels in brain and dorsal root ganglion in rat. Physiol Behav 105(3):683–692. doi: 10.1016/j.physbeh.2011.10.005 CrossRefPubMedGoogle Scholar
- 8.Dasdag S, Akdag MZ, Erdal ME, Erdal N, Ay OI, Ay ME, Yilmaz SG, Tasdelen B, Yegin K (2015) Effects of 2.4 GHz radiofrequency radiation emitted from Wi-Fi equipment on microRNA expression in brain tissue. Int J Radiat Biol 91(7):555–561. doi: 10.3109/09553002.2015.1028599 CrossRefPubMedGoogle Scholar
- 17.Darabi SAS, Firoozabadi SM, Tabatabaie KR, Ghabaee M (2011) EEG changes during exposure to extremely low frequency magnetic field on a small area of brain. Koomesh 12(2):167–174Google Scholar
- 18.Shafiei SA, Firoozabadi SM, Tabatabaie KR, Ghabaee M (2014) Investigation of EEG changes during exposure to extremely low-frequency magnetic field to conduct brain signals. Neurol Sci: Off J Ital Neurol Soc Ital Soc Clin Neurophysiol 35(11):1715–1721. doi: 10.1007/s10072-014-1819-0 CrossRefGoogle Scholar