Clinical and MRI improvement in a case of progressive multifocal leukoencephalopathy

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  1. 1.

    Weissert R (2011) Progressive multifocal leukoencephalopathy. J Neuroimmunol 23:73–77

    Article  Google Scholar 

  2. 2.

    Berger JR, Aksamit AJ, Clifford DB, Davis L, Koralnik IJ, Sejvar JJ, Bartt R, Major EO, Nath A (2013) PML diagnostic criteria. Consensus statement from the AAN neuroinfectious disease section. Neurology 80:1430–1438

    Article  PubMed  PubMed Central  Google Scholar 

  3. 3.

    Tan K, Roda R, Ostrow L, McArthur J, Nath A (2009) PML-IRIS in patients with HIV infection: clinical manifestations and treatment with steroids. Neurology 72:1458–1464

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  4. 4.

    Reilmann R, Imai T, Ringelstein EB, Gaubitz M, Niederstadt TU, Paulus W, Husstedt IW (2005) Remission of progressive multifocal leucoencephalopathy in SLE after treatment with cidofovir: a 4 year follow up. J Neurol Neurosurg Psychiatry 76:1304–1305

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  5. 5.

    Clifford DB, De Luca A, Simpson DM, Arendt G, Giovannoni G, Nath A (2010) Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: lessons from 28 cases. Lancet Neurol 9:438–446

    CAS  Article  PubMed  Google Scholar 

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Authors gratefully thank Doctor Daniele Giuseppe Romano for his help in the brain MRI evaluation.

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Correspondence to Alessandra Rufa.

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None. All authors have approved the final article. Patient’s anonymity was protected in this case report.

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Tirelli, L., Rosini, F., Rufa, A. et al. Clinical and MRI improvement in a case of progressive multifocal leukoencephalopathy. Neurol Sci 38, 1517–1519 (2017).

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  • Systemic Lupus Erythematosus
  • Systemic Lupus Erythematosus Patient
  • Progressive Multifocal Leukoencephalopathy
  • Mirtazapine
  • Natalizumab