Abstract
Multiple sclerosis (MS) is a long-lasting neurological disease with onset in young adult age. Patients with MS are less active than healthy people, and their sedentary lifestyle might lead to secondary diseases or worsening of symptoms, disability and quality of life. In the study, we evaluated the attitude of physical activity (PA) of a group of MS patients and the differences in practice PA before and after the diagnosis. A randomly recruited group of patients with MS fulfilled a questionnaire about their attitudes towards PA before the onset and after the diagnosis of the disease. Clinical and demographic data were recorded. Out of 118 patients, 37 % practiced PA only before the diagnosis, 9 % only after and 52 % during both periods. After the diagnosis, 64 % of participants noted some negative differences in PA, in particular less physical resistance and worsening of symptoms, and 38 % stopped PA. However, patients referred benefits from PA after diagnosis. Individual exercises rather than group activities were preferred after diagnosis. Only 26 % of patients knew that adapted PA existed and the differences between adapted PA and classic physiotherapy. We observed a reduction in the practice of PA in patients after the diagnosis of MS, in particular for disease-related reasons. Nevertheless, active patients referred benefits from PA. It is important to know the point of view of patients towards developing individualized training programs. In this way, it could be possible to achieve more benefits from PA and reduce the negative effects.
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References
Compston A, Coles A (2008) Multiple sclerosis. Lancet 372(9648):1502–1517
MacAllister WS, Krupp LB (2005) Multiple sclerosis-related fatigue. Phys Med Rehabil Clin N Am 16(2):483–502
Chiaravalloti ND, DeLuca J (2008) Cognitive impairment in multiple sclerosis. Lancet Neurol 7(12):1139–1145
Benito-León J, Morales JM, Rivera-Navarro J, Mitchell A (2003) A review about the impact of multiple sclerosis on health-related quality of life. Disabil Rehabil 25:1291–1303
Mitchell AJ, Benito-León J, Gonzalez JM, Rivera-Navarro J (2005) Quality of life and its assessment in multiple sclerosis: integrating physical and psychological components of wellbeing. Lancet Neurol 4(9):556–566 Review
Miller A, Dishon S (2006) Health-related quality of life in multiple sclerosis: the impact of disability, gender and employment status. Qual Life Res 15:259–271
Hincapie-Zapata ME, Suarez-Escudero JC, Pineda-Tamayo R, Anaya JM (2009) Quality of life in multiple sclerosis and other chronic autoimmune and non-autoimmune diseases. Rev Neurol 48(5):225–230
Motl RW, McAuley E, Snook EM (2005) Physical activity and multiple sclerosis: a meta-analysis. Mult Scler 11(4):459–463
Kalron A, Achiron A, Dvir Z (2011) Muscular and gait abnormalities in persons with early onset multiple sclerosis. J Neurol Phys Ther 35(4):164–169
Motl RW, Goldman M (2011) Physical inactivity, neurological disability, and cardiorespiratory fitness in multiple sclerosis. Acta Neurol Scand 123(2):98–104
Motl RW, McAuley E, Snook EM, Gliottoni RC (2009) Physical activity and quality of life in multiple sclerosis: intermediary roles of disability, fatigue, mood, pain, self-efficacy and social support. Psychol Health Med 14(1):111–124
Doring A, Pfueller CF, Paul F, Dorr J (2009) Exercise in multiple sclerosis – an integral component of disease management. EPMA J 3(1):2
Cocco E, Sardu C, Massa R, Mamusa E, Musu L, Ferrigno P et al (2009) Epidemiology of multiple sclerosis in south-western Sardinia. Mult Scler 17(11):1282–1289
Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L et al (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”. Ann Neurol 58(6):840–846 Review
Kurtzke JF (2005) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33(11):1444–1452
Ponichtera-Mulcare JA (2005) Exercise and multiple sclerosis. Med Sci Sports Exerc 25(4):451–465 Review
Freal JE, Kraft GH, Coryell JK (1984) Symptomatic fatigue in multiple sclerosis. Arch Phys Med Rehabil 65(3):135–138
Benito-León J (2011) Physical activity in multiple sclerosis: the missing prescription. Neuroepidemiology 36(3):192–193
Smith RM, Adeney-Steel M, Fulcher G, Longley WA (2006) Symptom change with exercise is a temporary phenomenon for people with multiple sclerosis. Arch Phys Med Rehabil 87(5):723–727
Gallien P, Nicolas B, Robineau S, Pétrilli S, Houedakor J, Durufle A (2007) Physical training and multiple sclerosis. Annales de rédaption et médicine pysique 50:373–376
Comi G, Leocani L, Rossi P, Colombo B (2001) Physiopathology and treatment of fatigue in multiple sclerosis. J Neuronal 248:174–179
Sandroff BM, Dlugonski D, Weikert M, Suh Y, Balantrapu S, Motl RW (2012) Physical activity and multiple sclerosis: new insights regarding inactivity. Acta Neurol Scand. doi:10.1111/j.1600-0404.2011.01634.x
Motl RW, Snook EM (2008) Physical activity, self-efficacy, and quality of life in multiple sclerosis. Ann Behav Med 35(1):111–115
Motl RW, McAuley E, Wynn D, Sandroff B, Suh Y (2013) Physical activity, self-efficacy, and health-related quality of life in persons with multiple sclerosis: analysis of associations between individual-level changes over one year. Qual Life Res 22(2):253–261
Andreasen AK, Stenager E, Dalgas A (2011) The effect of exercise therapy on fatigue in multiple sclerosis. Mult Scler 17(9):1041–1054
Motl RW, Sandroff BM, Benedict RH (2011) Cognitive dysfunction and multiple sclerosis: developing a rationale for considering the efficacy of exercise training. Mult Scler 17(9):1034–1040
Suh Y, Motl RW, Mohr DC (2010) Physical activity, disability, and mood in the early stage of multiple sclerosis. Disabil Health J 3(2):93–98
Motl RW, Gosney JL (2008) Effect of exercise training on quality of life in multiple sclerosis: a meta-analysis. Mult Scler 14(1):129–135
Rietberg MB, Brooks D, Uitdehaag BMJ (2005) Exercise therapy for multiple sclerosis. Cochrane Database Syst Rev (1):CD003980
Rampello A, Franceschini M, Piepoli M, Antenucci R, Lenti G, Olivieri D et al (2007) Effect of aerobic training on walking capacity and maximal exercise tolerance in patients with multiple sclerosis: a randomized crossover controlled study. Phys Ther 87(5):545–555
Gold SM, Schulz KH, Hartmann S, Mladek M, Lang UE, Hellweg R et al (2003) Basal serum levels and reactivity of nerve growth factor and brain-derived neurotrophic factor to standardized acute exercise in multiple sclerosis and controls. J Neuroimmunol 138(1–2):99–105
Golzari Z, Shabkhiz F, Soudi S, Kordi MR, Hashemi SM (2010) Combined exercise training reduces IFN-γ and IL-17 levels in the plasma and the supernatant of peripheral blood mononuclear cells in women with multiple sclerosis. Int Immunopharmacol 10(11):1415–1419
Dalgas U, Stenager E (2012) Exercise and disease progression in multiple sclerosis: can exercise slow down the progression of multiple sclerosis? Ther Adv Neurol Disord 5(2):81–95
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Frau, J., Coghe, G., Lorefice, L. et al. Attitude towards physical activity in patients with multiple sclerosis: a cohort study. Neurol Sci 36, 889–893 (2015). https://doi.org/10.1007/s10072-015-2100-x
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DOI: https://doi.org/10.1007/s10072-015-2100-x