Skip to main content

The effect of vagus nerve stimulation on migraine in patient with intractable epilepsy: case report

This is a preview of subscription content, access via your institution.



Vagus nerve stimulation




Interictal epileptiform discharges


Single photon emission computed tomography




Magnetic resonance imaging


Video EEG


Visual analogue scale


Solitary tract nucleus


Locus coeruleus


  1. Penry JK, Dean JC (1990) Prevention of intractable partial seizures by intermittent vagal stimulation in humans: preliminary results. Epilepsia 31(Suppl 2):S40–S43

    Article  PubMed  Google Scholar 

  2. Hord ED, Evans MS, Mueed S, Adamolekun B, Naritoku DK (2003) The effect of vagus nerve stimulation on migraines. J Pain 4(9):530–534 [pii: S1526590003008095]

    Article  PubMed  Google Scholar 

  3. Sadler RM, Purdy RA, Rahey S (2002) Vagal nerve stimulation aborts migraine in patient with intractable epilepsy. Cephalalgia 22(6):482–484. doi:10.1046/j.1468-2982.2002.00387.x

    Article  PubMed  CAS  Google Scholar 

  4. Mauskop A (2005) Vagus nerve stimulation relieves chronic refractory migraine and cluster headaches. Cephalalgia 25(2):82–86. doi:10.1111/j.1468-2982.2005.00611.x

    Article  PubMed  CAS  Google Scholar 

  5. Lenaerts ME, Oommen KJ, Couch JR, Skaggs V (2008) Can vagus nerve stimulation help migraine? Cephalalgia 28(4):392–395. doi:10.1111/j.1468-2982.2008.01538.x

    Article  PubMed  CAS  Google Scholar 

  6. Wang H, Chen X, Lin Z, Shao Z, Sun B, Shen H, Liu L (2009) Long-term effect of vagus nerve stimulation on interictal epileptiform discharges in refractory epilepsy. J Neurol Sci 284(1–2):96–102. doi:10.1016/j.jns.2009.04.012

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.

Author information

Authors and Affiliations


Corresponding author

Correspondence to Gordan Grahovac.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Basic, S., Sporis, D., Chudy, D. et al. The effect of vagus nerve stimulation on migraine in patient with intractable epilepsy: case report. Neurol Sci 34, 797–798 (2013).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI:


  • Epilepsy therapy
  • Chronic pain
  • Headaches
  • Migraine
  • Vagus nerve stimulation