Neurological Sciences

, Volume 33, Supplement 1, pp 81–85 | Cite as

Migraine and metabolism

  • G. Casucci
  • V. Villani
  • D. Cologno
  • F. D’Onofrio


Migraine is a chronic disorder with complex pathophysiology involving both neuronal and vascular mechanisms. Migraine is associated with an increased risk of vascular disorders, such as stroke and coronary heart disease. Obesity and diabetes are metabolic disorders with a complex association with migraine. Insulin resistance, which represents the main causal factor of diseases involved in metabolic syndrome, is more common in patients with migraine. A better understanding of the relationship between metabolic syndrome and migraine may be of great clinical interest for migraine management.


Migraine Metabolic syndrome Obesity Vascular disease 


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • G. Casucci
    • 1
  • V. Villani
    • 2
    • 3
  • D. Cologno
    • 4
  • F. D’Onofrio
    • 5
  1. 1.Casa di Cura S. FrancescoTelese Terme, BNItaly
  2. 2.Department Neurology and PsychiatryUniversity SapienzaRomeItaly
  3. 3.Department NeurologyNational Cancer Institute Regina ElenaRomeItaly
  4. 4.Institute of Clinical Neurophysiology, Department of NeuroscienceAzienda Ospedaliero-Universitaria, OO.RR.FoggiaItaly
  5. 5.Neurology Unit, “S.G. Moscati” HospitalAvellinoItaly

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