Non-pharmacological approach to migraine prophylaxis: part II

Abstract

Acupuncture has been used to both prevent and treat diseases for over 3,000 years. Recently, a Cochrane review on its use in migraine concluded that acupuncture is effective and should be considered as a prophylactic measure for patients with frequent or insufficiently controlled migraine attacks. In contrast, there is no clear evidence to support or refute the use of homeopathy in the management of migraine. Among vitamins and other supplements, riboflavin and coenzyme Q10 significantly decreased the frequency of migraine attacks. Alpha lipoic acid also reduced migraine frequency, albeit not significantly as compared to placebo. The prophylactic efficacy of magnesium, particularly for children and menstrually related migraine, has recently been substantiated. Among the herbal remedies, butterbur significantly decreases attack frequency, whereas the efficacy of feverfew was not confirmed in a Cochrane review, probably because of the 400% variations in the dosage of its active principle. Finally, ginkgolide B has proved significantly effective in controlling migraine with aura and pediatric migraine in uncontrolled studies that need a confirmation.

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References

  1. 1.

    Gaul C, Eismann R, Schmidt T, May A, Leinisch E, Wieser T, Evers S, Henkel K, Franz G, Zierz S (2009) Use of complementary and alternative medicine in patients suffering from primary headache disorders. Cephalalgia 29:1069–1078

    PubMed  Article  CAS  Google Scholar 

  2. 2.

    Melchart D, Linde K, Fisher P, Berman B, White A, Vickers A, Allais G (2001) Acupuncture for idiopathic headache. Cochrane Database Syst Rev (1):CD001218

  3. 3.

    Linde K, Allais G, Brinkhaus B, Manheimer E, Vickers A, White AR (2009) Acupuncture for migraine prophylaxis. Cochrane Database Syst Rev (1):CD001218

  4. 4.

    Owen JM, Chom DC, Green BN (2004) Homeopathic treatment of headaches: a systematic review of the literature. J Chiropr Med 3(2):45–52

    PubMed  Article  Google Scholar 

  5. 5.

    Schoenen J, Jacquy J, Lenaerts M (1998) Effectiveness of high-dose riboflavin in migraine prophylaxis—a randomized controlled trial. Neurology 50:466–470

    PubMed  CAS  Google Scholar 

  6. 6.

    Sandor PS, Di Clemente L, Coppola G, Saenger U, Fumal A, Magis D, Seidel L, Agosti RM, Schoenen J (2005) Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology 64:713–715

    PubMed  CAS  Google Scholar 

  7. 7.

    Hershey AD, Powers SW, Vockell AL, Lecates SL, Ellinor PL, Segers A, Burdine D, Manning P, Kabbouche MA (2007) Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache 47(1):73–80

    PubMed  Article  Google Scholar 

  8. 8.

    Magis D, Ambrosini A, Sándor P, Jacquy J, Laloux P, Schoenen J (2007) A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis. Headache 47:52–57

    PubMed  Article  Google Scholar 

  9. 9.

    Grazzi L, Andrasik F, Usai S, Bussone G (2007) Magnesium as a preventive treatment for paediatric episodic tension-type headache: results at 1-year follow-up. Neurol Sci 28(3):148–150

    PubMed  Article  CAS  Google Scholar 

  10. 10.

    Sun-Edelstein C, Mauskop A (2009) Role of magnesium in the pathogenesis and treatment of migraine. Expert Rev Neurother 9(3):369–379

    PubMed  Article  CAS  Google Scholar 

  11. 11.

    Agosti R, Duke RK, Chrubasik JE, Cheubasik S (2006) Effectiveness of Petasites hybridus preparations in the prophylaxis of migraine: a systematic review. Phytomedicine 13:743–746

    PubMed  Article  CAS  Google Scholar 

  12. 12.

    Kaufeler R, Polasek W, Brattstrom A, Koetter U (2006) Efficacy and safety of butterbur herbal extract Ze 339 in seasonal allergic rhinitis: postmarketing surveillance study. Adv Ther 23:373–384

    PubMed  Article  Google Scholar 

  13. 13.

    Pittler MH, Ernst E (2004) Feverfew for preventing migraine. Cochrane Database Syst Rev (1):CD002286

  14. 14.

    Diener HC, Pfaffenrath V, Schnitker J, Friede M, Henneicke-von Zepelin HH (2005) Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention—a randomized, double-blind, multicentre, placebo-controlled study. Cephalalgia 25:1031–1041

    PubMed  Article  CAS  Google Scholar 

  15. 15.

    D’Andrea G, Bussone G, Allais G, Aguggia M, D’Onofrio F, Maggio M, Moschiano F, Saracco MG, Terzi MG, Petretta V, Benedetto C (2009) Efficacy of Ginkgolide B in the prophylaxis of migraine with aura. Neurol Sci 30(Suppl 1):S121–S124

    PubMed  Article  Google Scholar 

  16. 16.

    Usai S, Grazzi L, Andrasik F, Bussone G (2010) An innovative approach for migraine prevention in young age: a preliminary study. Neurol Sci 31(Suppl 1). doi:10.1007/s10072-010-0321-6

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The authors declare that they have no conflict of interest related to the publication of this article.

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Correspondence to Gianni Allais.

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Schiapparelli, P., Allais, G., Castagnoli Gabellari, I. et al. Non-pharmacological approach to migraine prophylaxis: part II. Neurol Sci 31, 137–139 (2010). https://doi.org/10.1007/s10072-010-0307-4

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Keywords

  • Acupuncture
  • Complementary therapies
  • Dietary supplements
  • Migraine
  • Phytotherapy