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Novel nutraceutical delivery system utilizing a bigel formulated with sesame oil, kokum butter, and pectin

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Abstract

This study delineates biobased foods. Curcumin (CRU) delivery modules were studied using pectin gel, Sesame oil (SO), and Kokum butter (KB) oleogel (OG). SB1, the control, has 10% OG. The pectin gel between 10 and 50% oleogel were emulsified by 2.5% tween 80. Surface, physical, chemical, and physiochemical properties of prepared bigels were examined. Microscopic studies show biphasic feature. With OG content, FTIR shows hydrogen bonding increasing and decreasing. XRD confirmed gel amorphousness. Stress relaxation indicated 10% control bigel had considerably less strength. Bigel impedance factors increased considerably with OG content, according to impedance profiles. The moisture study found that replacing hydro phase with OG phase in formulations reduced moisture content from 10 to 50%. Less CRU released from 20 to 50% bigel matrices than 10% during in vitro studies. Acidic pH hindered polymer relaxation, altering release behaviour. Overall, the bigels were studied and shown to regulate oral CRU administration.

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Acknowledgements

We sincerely acknowledge the Director of National Institute of Technology Andhra Pradesh (NIT AP), National Institute of Technology Rourkela and Institute of Pharmacy and Technology, Salipur, Odisha for providing facilities to carry out the Ph.D. work. This paper forms a part of the Ph.D. thesis work submitted to the National Institute of Technology Andhra Pradesh, Tadepalligudem, Andhra Pradesh, India.

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Authors and Affiliations

  1. Department of Biotechnology, National Institute of Technology Andhra Pradesh, Tadepalligudem, Andhra Pradesh, India

    Dheerendra Kumar Suman & Rajeswara Reddy Erva

  2. Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, India

    Kunal Pal

  3. Department of Pharmaceutics, Institute of Pharmacy and Technology, Salipur, Odisha, India

    Biswaranjan Mohanty

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  1. Dheerendra Kumar Suman
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  2. Kunal Pal
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  4. Rajeswara Reddy Erva
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Correspondence to Biswaranjan Mohanty or Rajeswara Reddy Erva.

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Suman, D.K., Pal, K., Mohanty, B. et al. Novel nutraceutical delivery system utilizing a bigel formulated with sesame oil, kokum butter, and pectin. Food Sci Biotechnol (2024). https://doi.org/10.1007/s10068-024-01559-3

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  • DOI: https://doi.org/10.1007/s10068-024-01559-3

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