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Lactic acid bacteria-malted vinegar: fermentation characteristics and anti-hyperlipidemic effect

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Abstract

In this study, the fermentation characteristics and functional properties of lactic acid bacteria-malted vinegar (LAB-MV) were investigated during the fermentation period. Changes in the components (organic acids, free sugars, free amino acids, β-glucan, and gamma-aminobutyric acid (GABA)) of MV (BWAF0d, BWAF10d, BWAF20d) and LAB-MV (LBWAF0d, LBWAF10d, LBWAF20d) were analyzed according to the fermentation time. The amounts of β-glucan and GABA in LBWAF20d were greater than those in BWAF20d (122.00 μg/mL, 83.06 μg/mL and 531.00 μg/mL, 181.31 μg/mL, respectively). The ACE1 and HMG-CoA reductase inhibitory activities of LBWAF20d were 98.16% (1/20 dilution factor, DF) and 91.01% (1/25 DF), respectively. The lipid accumulation ratio and total cholesterol levels in HepG2 cells treated with LBWAF20d (1/200 DF) were reduced by 45.85% and 54.48%, respectively, compared to those in the untreated group. These results suggest that LAB-MV, which comprises barley wine manufactured from LAB and yeast, may improve hepatic lipid metabolism.

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Acknowledgements

This research was supported by Local Strategic Food Industry Promote Program, Ministry of Agriculture Food and Rural Affairs, Republic of Korea (MIFI 2022-01). We would like to thank Editage (www.editage.co.kr) for English language editing.

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Authors and Affiliations

  1. Department of Food Science and Technology, Jeonbuk National University, 567, Baekje-Daero, Deokjin-Gu, Jeonju, Jeonbuk, 54896, Republic of Korea

    So-Won Jang, Hyeon Hwa Oh, Kyung Eun Moon, Byung-Min Oh & Geun-Seoup Song

  2. Microbial Institute for Fermentation Industry (MIFI), Sunchang, 56048, Republic of Korea

    Do-Youn Jeong

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  1. So-Won Jang
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  2. Hyeon Hwa Oh
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Correspondence to Geun-Seoup Song.

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Jang, SW., Oh, H.H., Moon, K.E. et al. Lactic acid bacteria-malted vinegar: fermentation characteristics and anti-hyperlipidemic effect. Food Sci Biotechnol 33, 1425–1436 (2024). https://doi.org/10.1007/s10068-024-01528-w

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