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Mechanistic insights on burdock (Arctium lappa L.) extract effects on diabetes mellitus

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Abstract

Diabetes mellitus (DM) type 2 is amongst the most common chronic diseases, being responsible for various problems in humans and contributing to increased mortality rates worldwide. Fructooligosaccharide, which can be produced from the roots of burdock (Arctium lappa L.), has been shown to have a wide range of pharmacological proprieties, including antiviral, anti-inflammatory, hypolipidemic, and antidiabetic effects. Moreover, burdock also contains chlorogenic acid, which has been used in traditional medicine as an antioxidant. Considering its natural origin and minimal toxicity, burdock fructooligosaccharides (BFO) has gained considerable attention from researchers owing its wide, efficient, and beneficial action against DM. Although the effectiveness of fructooligosaccharide and chlorogenic acid has been extensively discussed, limited information is available on the application of burdock for DM treatment. In this review, we discuss the beneficial contributions, and the recent in vitro and in vivo analytical findings on A. lappa extract as DM therapy.

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Acknowledgements

We would like to thanks Food Science and Biotechnology for its special issue “Polyphenols and Health” and giving us this opportunity to write this review. We did not receive any fund for this review.

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  1. Department of Integrative Food, Bioscience and Biotechnology, Graduate School of Chonnam, National University, Gwangju, 61186, South Korea

    Shakti Chandra Mondal & Jong-Bang Eun

  2. Department of Food Processing and Preservation, Hajee Mohammad Danesh Science and Technology University, Dinajpur, 5200, Bangladesh

    Shakti Chandra Mondal

  3. Department of Food Science and Technology, College of Agriculture and Life Sciences, Chonnam National University, Rm#110, CALS Bldg 3, Gwangju, 61186, South Korea

    Jong-Bang Eun

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Mondal, S.C., Eun, JB. Mechanistic insights on burdock (Arctium lappa L.) extract effects on diabetes mellitus. Food Sci Biotechnol 31, 999–1008 (2022). https://doi.org/10.1007/s10068-022-01091-2

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