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Effect of agave fructans on the production of short chain fatty acid in mice

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Abstract

The aim of this study was to evaluate the effect of agave fructans on short chain fatty acid (SCFA) production in mice (C57BL/6). Animals were randomly divided into three groups (n = 8): control group (CG), fructans from Agave tequilana group (FG) (55 g per day/kg of body weight), and oligrofructose group (OG) (55 g per day/kg of body weight). Treatments were administered oral via for 6 weeks. After 24 days of treatment (phase 1), both treated groups exhibited elevated levels of acetic (12%) and propionic (FG 66% and OG 38%) acids in comparison with the CG. After 42 days of treatment (phase 2), FG had higher concentrations of acetic (33%) and propionic (73%) acids than the CG; while OG exhibited higher levels of butyric (12%) and propionic (35%) acids compared with the CG. Fructans from Agave tequilana improve the production of SCFA in mice, suggesting a prebiotic activity.

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Acknowledgements

This project was financially supported by Strengthening and Development of Scientific and Technological Infrastructure Program (Grants No. 253333 and 224651).

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Authors and Affiliations

  1. TECNM/Instituto Tecnológico de Durango, Felipe Pescador 1830 Ote., 34080, Durango, Dgo., Mexico

    Silvia M. González-Herrera, Nuria E. Rocha-Guzmán & Olga M. Rutiaga-Quiñones

  2. Unidad de Investigación Biomédica, Delegación Durango, Instituto Mexicano del Seguro Social, Durango, Mexico

    Luis E. Simental-Mendía & Claudia I. Gamboa-Gómez

  3. Departamento de Biotecnología y Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN, Campus Guanajuato, Apartado Postal 629, 36500, Irapuato, Gto., Mexico

    Mercedes G. López

  4. Food Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Saltillo, Mexico

    Raúl Rodríguez-Herrera

Authors
  1. Silvia M. González-Herrera
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  2. Luis E. Simental-Mendía
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  3. Mercedes G. López
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  4. Nuria E. Rocha-Guzmán
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  5. Olga M. Rutiaga-Quiñones
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  6. Raúl Rodríguez-Herrera
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  7. Claudia I. Gamboa-Gómez
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Correspondence to Claudia I. Gamboa-Gómez.

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All institutional and national guidelines for the care and use of laboratory animals were followed.

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González-Herrera, S.M., Simental-Mendía, L.E., López, M.G. et al. Effect of agave fructans on the production of short chain fatty acid in mice. Food Sci Biotechnol 28, 1493–1498 (2019). https://doi.org/10.1007/s10068-019-00572-1

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