The objective of this study was to develop new drug delivery systems (DDS) and nutrient delivery systems (NDS), using starch as a carrier material for infusion technology. Corn, waxy rice, non-waxy rice, and potato starches were used as carrier materials. Sodium fluorescein was used as an infusion material for easy detection. Each starch suspension with sodium fluorescein was reacted in a water bath at 40, 50, and 60 °C for 30 min. After each reaction, the concentration of sodium fluorescein in the supernatant was measured using a fluorescence detector. Precipitated starch was observed using fluorescence microscopy. About 70% of sodium fluorescein infused in waxy rice and corn starches at 60 °C. Additionally, the granules of these two starches were luminous by green light when exposed to a fluorescence detector, suggesting that corn and waxy rice starches can be used as carrier materials in infusion technology for DDS and NDS.
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This research was supported by the Main Research Program (E0164800-03) of the Korea Food Research Institute (KFRI) funded by the Ministry of Science, ICT & Future Planning.
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Choi, SH., Kim, Hy., Oh, SM. et al. Infusion efficiency of sodium fluorescein into various starches. Food Sci Biotechnol 28, 99–102 (2019). https://doi.org/10.1007/s10068-018-0455-5
- Drug delivery system
- Nutrient delivery system
- Sodium fluorescein