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Infusion of catechin into native corn starch granules for drug and nutrient delivery systems

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Abstract

Hydrophilic nutrients, a water insoluble drug, and amino acids were used as infusion materials for analysis w ith HPLC and a micro-plate reader. Only catechin, gallic a cid, and caffeine infused into native corn starch granules. While catechin remained in the native corn starch granule after several washing steps, infused caffeine and gallic acid were washed out. A release study was also performed using pancreatin α-amylase. Infused catechin was successfully released when native corn starch granules were decomposed. Infusion and maintenance of catechin in native corn starch granules were probably due to a unique chemical structure of the benzene-tetrahydropyran group that affected interactions with starch. However, experiments using epicatechin and rutin indicated that the benzenetetrahydropyran group structure may not have been the only reason for infusion of guest materials. The 3 dimensional structure of the benzene-tetrahydropyran group probably also influenced infusion of materials.

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Authors and Affiliations

  1. Department of Food Science and Biotechnology, Institute of Life Science and Resources, Kyung Hee University, Yongin, Gyeonggi, 17104, Korea

    Saem Han, Seung-Hyun Choi, Wooki Kim, Byung-Yong Kim & Moo-Yeol Baik

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  1. Saem Han
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  2. Seung-Hyun Choi
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  3. Wooki Kim
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Correspondence to Moo-Yeol Baik.

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Han, S., Choi, SH., Kim, W. et al. Infusion of catechin into native corn starch granules for drug and nutrient delivery systems. Food Sci Biotechnol 24, 2035–2040 (2015). https://doi.org/10.1007/s10068-015-0270-1

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  • DOI: https://doi.org/10.1007/s10068-015-0270-1

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