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Dietary supplementation with a fermented barley and soybean mixture attenuates UVB-induced skin aging and dehydration in hairless mouse skin

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Abstract

This study evaluated the protective effects of dietary supplementation with a fermented barley and soybean mixture (BS) on ultraviolet (UV) B-induced photoaging in hairless mice. Skin aging-related parameters and protein levels related to skin wrinkles and moisturization in mice were analyzed. The BS reduced wrinkle formation, skin thickening, transepidermal water loss, and matrix metalloproteinases-1 expression in skin. Skin hydration and pH were increased in the BS group. BS attenuated filaggrin expression as well as free amino acid and glycerol production. BS increased superoxide dismutase activity as well as increased expression of nuclear factor (erythroid-derived 2)-like 2, procollagen type-I, and decreased erythema. These results suggest that BS protects against photoaging induced by UVB in vivo, indicating the potential of such mixtures as anti-photoaging dietary supplementation.

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Authors and Affiliations

  1. Graduate School of East-West Medical Science, Kyung Hee University Global Campus, Yongin, Gyeonggi, 446-701, Korea

    Oh Wook Kwon

  2. College of Pharmacy, Gachon University, Incheon, 406-799, Korea

    Ramu Venkatesan, Moon Ho Do, Eunhee Ji & Sun Yeou Kim

  3. Gachon Medical Research Institute, Gil Medical Center, Incheon, 405-760, Korea

    Sun Yeou Kim

  4. Gachon Institute of Pharmaceutical Science, Gachon University, Incheon, 406-799, Korea

    Sun Yeou Kim

  5. Sempio Fermentation Research Center, Osong, Chungbuk, 363-954, Korea

    Dong Woon Cho

  6. WCU Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, 151-742, Korea

    Ki Won Lee

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  1. Oh Wook Kwon
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Correspondence to Sun Yeou Kim.

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Kwon, O.W., Venkatesan, R., Do, M.H. et al. Dietary supplementation with a fermented barley and soybean mixture attenuates UVB-induced skin aging and dehydration in hairless mouse skin. Food Sci Biotechnol 24, 705–715 (2015). https://doi.org/10.1007/s10068-015-0092-1

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  • DOI: https://doi.org/10.1007/s10068-015-0092-1

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