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Korean red ginseng combined with nattokinase ameliorates dyslipidemia and the area of aortic plaques in high cholesterol-diet fed rabbits

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Abstract

Male white rabbits were fed a high cholesterol diet supplemented with red ginseng (RG) or red ginseng plus nattokinase (RGNK). RG and RGNK significantly reduced increased serum triglycerides levels and aortic plaque area in a hypercholesterol diet fed rabbits. Moreover, only RGNK reduced hepatic cholesterol and cholesteryl ester transfer protein activity levels. Therefore, the present study suggests RGNK might be a potential therapeutic approach for atherogenesis.

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Authors and Affiliations

  1. Department of Herbal Pharmaceutical Science, Graduate School of Joongbu University, Chungnam, 312-702, Korea

    Shin-Jyung Kang

  2. Department of Food and Nutrition, Kyunghee University, Seoul, 130-701, Korea

    Yunsook Lim

  3. The Graduate School of Alternative Medicine, Kyunggi University, Seoul, 120-837, Korea

    Ae-Jung Kim

Authors
  1. Shin-Jyung Kang
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  2. Yunsook Lim
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Correspondence to Ae-Jung Kim.

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Kang, SJ., Lim, Y. & Kim, AJ. Korean red ginseng combined with nattokinase ameliorates dyslipidemia and the area of aortic plaques in high cholesterol-diet fed rabbits. Food Sci Biotechnol 23, 283–287 (2014). https://doi.org/10.1007/s10068-014-0039-y

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  • DOI: https://doi.org/10.1007/s10068-014-0039-y

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